1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid

SIAL/14510 - ≥96.0% (HPLC)

Synonym: BAPTA; Ethylenedioxybis(o-phenylenenitrilo)tetraacetic acid

CAS Number: 85233-19-8
Empirical Formula (Hill Notation): C₂₂H₂₄N₂O₁₀
Molecular Weight: 476.43
MDL Number: MFCD00036255
Linear Formula: C₂₂H₂₄N₂O₁₀
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-14510-100MG-F	100 mg	$86.40 1/EA		Add To Favorites
45-14510-250MG-F	250 mg	$205.00 1/EA		Add To Favorites
45-14510-1G-F	1 g	$255.00 1/EA		Add To Favorites
45-14510-50G-F	50 g	$3510.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥96.0% (HPLC)
fluorescence	λ_ex 251 nm; λ_em 363 nm (pH 8.0 Highly selective calcium chelating reagent. Suitable for the spectrophotometric monitoring of Ca2+ levels)
	λ_ex 274 nm; λ_em 363 nm (With Calcium)
form	powder
InChI	1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)
InChI key	FTEDXVNDVHYDQW-UHFFFAOYSA-N
Quality Level	200
SMILES string	OC(=O)CN(CC(O)=O)c1ccccc1OCCOc2ccccc2N(CC(O)=O)CC(O)=O
storage temp.	2-8°C

Application:	1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′′-tetraacetic acid was used for the spectrophotometric monitoring of Ca²⁺ levels. It may be used as chelator of cytosolic Ca²⁺ to investigate the effect of methoxychlor on cytosolic free Ca²⁺concentrations and apoptosis in HA59T human hepatoma cells.
Application:	Highly selective calcium chelating reagent. Suitable for the spectrophotometric monitoring of Ca²⁺ levels
General description:	1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid is a highly selective calcium chelating reagent. Effect of microinjected calcium-loaded 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid (CaBAPTA) on cell-to-cell diffusion of carboxyfluorescein has been studied in staminal hairs of Setcreasea purpurea. It is reported to be a metabolite of 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetra(acetoxymethyl ester) (BAPTA-AM) in rat urine.

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥96.0% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352112

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