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Bis(cyclohexanone)oxaldihydrazone

SIAL/14690 - for spectrophotometric det. of Cu, ≥99.0%

Synonym: Cuprizon; Cuprizone; Oxalic acid bis(cyclohexylidenehydrazide)

CAS Number: 370-81-0
Empirical Formula (Hill Notation): C14H22N4O2
Molecular Weight: 278.35
EC Number: 206-729-2
MDL Number: MFCD00001659
Linear Formula: C14H22N4O2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-14690-25G 25 g
$86.40
1/EA
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45-14690-100G 100 g
$251.00
1/EA
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assay ≥99.0%
  ≥99.0% (N)
form powder
InChI 1S/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2,(H,17,19)(H,18,20)
InChI key DSRJIHMZAQEUJV-UHFFFAOYSA-N
mp 210-214 °C
  210-214 °C (lit.)
quality for spectrophotometric det. of Cu
Quality Level 100 
SMILES string O=C(NN=C1CCCCC1)C(=O)NN=C2/CCCCC2
technique(s) UV/Vis spectroscopy: suitable
Application: Cuprizone (Bis(cyclohexanone)oxaldihydrazone) was used for toxic demyelination in the central nervous system in order to investigate the pathobiology of remyelination in the corpus callosum, so as to study the human demyelinating diseases such as multiple sclerosis. It was also used a model to study components of neuroinflammation.
General description: Cuprizone (Bis(cyclohexanone)oxaldihydrazone) is a physically unstable compound and is a well-known neurotoxic agent.
Other Notes: For the spectrophotometric determination of Cu(II)
Other Notes: In the presence of a copper salt, this ligand catalyzes Ullmann-type C-N bond forming reactions under mild, aqueous conditions.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99.0% (N); ≥99.0%
mp 210-214 °C (lit.); 210-214 °C
UNSPSC 41116105

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