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Serotonin

SIAL/14927 - analytical standard

Synonym: 3-(2-Aminoethyl)-5-hydroxyindole; 5-HT; 5-Hydroxytryptamine

CAS Number: 50-67-9
Empirical Formula (Hill Notation): C10H12N2O
Molecular Weight: 176.22
EC Number: 200-058-9
MDL Number: MFCD00055054
Linear Formula: C10H12N2O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-14927-25MG 25 mg
$121.00
1/EA
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assay ≥98.0% (HPLC)
format neat
grade analytical standard
impurities ≤1.0% water (calc. from elemental analysis)
InChI 1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
InChI key QZAYGJVTTNCVMB-UHFFFAOYSA-N
Quality Level 100 
shelf life limited shelf life, expiry date on the label
SMILES string OC1=CC=C(NC=C2CCN)C2=C1
storage temp. 2-8°C
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Application: This analytical standard can also be used as follows:• Electrochemical detection of serotonin in urine samples using a glassy carbon electrode (GCE) coated with multiwalled-carbon-nanotubes (MWCNT) doped with nickel, zinc, and iron oxide nanoparticles by a cyclic voltammetry procedure
• Development and validation of an ultra high-performance liquid chromatography-tandem mass spectrometry method to determine serotonin in raw and roasted samples of a variety of nuts, along with commercial nut products
• Designing of RuO2 nanowires/CeO2-AuNFs nanofibers/graphene oxide/functionalized multiwalled carbon nanotubes modified screen-printed carbon electrode for the multi-residue analysis of serotonin, dopamine, and ascorbic acid in cerebrospinal fluid and vitamin C tablet samples
• Construction of a low-cost glassy carbon electrode (GCE) modified with a nanoparticulate film of nanodiamonds and gold nanoparticles anchored to GCE using casein for the quantification of serotonin in urine samples
• Determination of serotonin in urine samples using a two-dimensional capillary isotachophoresis-capillary zone electrophoresis procedure coupled with tandem mass spectrometry (MS/MS)
General description: Serotonin, also known as 5-hydroxytryptamine, is an important biogenic monoamine neurotransmitter and a neuromodulator, found in the central nervous system. It is involved in regulating various physiological processes such as appetite, anxiety, sleep, mood, and blood pressure. A decrease in serotonin levels might result in disorders such as obesity, schizophrenia, and depression.
Other Notes: Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Purity ≥98.0% (HPLC)
Storage Temp. 2-8°C
UNSPSC 85151701

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