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Serotonin

SIAL/14927 - analytical standard

Synonym: 3-(2-Aminoethyl)-5-hydroxyindole; 5-HT; 5-Hydroxytryptamine

CAS Number: 50-67-9
Empirical Formula (Hill Notation): C10H12N2O
Molecular Weight: 176.22
EC Number: 200-058-9
MDL Number: MFCD00055054
Linear Formula: C10H12N2O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-14927-25MG 25 mg
$121.00
1/EA
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assay ≥95.0% (HPLC)
format neat
grade analytical standard
impurities ≤1.0% water (calc. from elemental analysis)
InChI 1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
InChI key QZAYGJVTTNCVMB-UHFFFAOYSA-N
Quality Level 100 
shelf life limited shelf life, expiry date on the label
SMILES string OC1=CC=C(NC=C2CCN)C2=C1
storage temp. 2-8°C
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Application: This analytical standard can also be used as follows:• Electrochemical detection of serotonin in urine samples using a glassy carbon electrode (GCE) coated with multiwalled-carbon-nanotubes (MWCNT) doped with nickel, zinc, and iron oxide nanoparticles by a cyclic voltammetry procedure
• Development and validation of an ultra high-performance liquid chromatography-tandem mass spectrometry method to determine serotonin in raw and roasted samples of a variety of nuts, along with commercial nut products
• Designing of RuO2 nanowires/CeO2-AuNFs nanofibers/graphene oxide/functionalized multiwalled carbon nanotubes modified screen-printed carbon electrode for the multi-residue analysis of serotonin, dopamine, and ascorbic acid in cerebrospinal fluid and vitamin C tablet samples
• Construction of a low-cost glassy carbon electrode (GCE) modified with a nanoparticulate film of nanodiamonds and gold nanoparticles anchored to GCE using casein for the quantification of serotonin in urine samples
• Determination of serotonin in urine samples using a two-dimensional capillary isotachophoresis-capillary zone electrophoresis procedure coupled with tandem mass spectrometry (MS/MS)
General description: Serotonin, also known as 5-hydroxytryptamine, is an important biogenic monoamine neurotransmitter and a neuromodulator, found in the central nervous system. It is involved in regulating various physiological processes such as appetite, anxiety, sleep, mood, and blood pressure. A decrease in serotonin levels might result in disorders such as obesity, schizophrenia, and depression.
Other Notes: Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Recommended products: Find a digital Reference Material for this product available on our online platform ChemisTwin®  for NMR. You can use this digital equivalent on ChemisTwin®  for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here  and start your free trial .
Purity ≥95.0% (HPLC)
Storage Temp. 2-8°C
UNSPSC 85151701

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