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N,O-Bis(trimethylsilyl)acetamide

SIAL/15269 - for GC derivatization, LiChropur, ≥98.5% (GC)

Synonym: BSA

CAS Number: 10416-59-8
Empirical Formula (Hill Notation): C8H21NOSi2
Molecular Weight: 203.43
EC Number: 233-892-7
MDL Number: MFCD00008270
Linear Formula: CH3C[=NSi(CH3)3]OSi(CH3)3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-15269-10X1ML 1 mL
$170.00
10/EA
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45-15269-5ML 5 mL
$53.70
1/EA
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45-15269-25ML 25 mL
$217.00
1/EA
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assay ≥98.5% (GC)
bp 71-73 °C/35 mmHg (lit.)
density 0.832 g/mL at 20 °C (lit.)
form liquid
grade for GC derivatization
InChI 1S/C8H21NOSi2/c1-8(9-11(2,3)4)10-12(5,6)7/h1-7H3/b9-8+
InChI key SIOVKLKJSOKLIF-CMDGGOBGSA-N
quality LiChropur
Quality Level 100 
reaction suitability reagent type: derivatization reagent
reaction type: Silylations
refractive index n20/D 1.417
  n20/D 1.417 (lit.)
SMILES string CC(O[Si](C)(C)C)=N/[Si](C)(C)C
technique(s) gas chromatography (GC): suitable
Application: Learn more in the Product Information 
Application: Suitable for the derivatization of 2-amino-2-dexoxyhexoses, ecdysones, hexosamines in glycosaminoglycans, 18-hydroxycorticosteroids, 15-Oxo-prostaglandin F2α, prostaglandins A,B and E and F, F, prostaglandins and metabolites, prostaglandins Emetabolites, sugar phosphates, steroids and testosterone.
General description: N,O-Bis(trimethylsilyl)acetamide is an excellent silylation reagent. For some sterically hindered primary or secondary nitro compounds, N,O-bis(trimethylsilyl)acetamide and BSTFA achieve better results than normal silylation conditions.
Legal Information: LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
Other Notes: Powerful silylating agent
Other Notes: Reagent for o-trimethylsilyl-aldono-1,4-lactones, trimethylsilyl and trimethylsilyl ether.
Purity ≥98.5% (GC)
bp 71-73 °C/35 mmHg (lit.)
Density 0.832 g/mL at 20 °C (lit.)
Refractive Index n20/D 1.417 (lit.); n20/D 1.417
UNSPSC 41116105

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