Glycine
SIAL/15527 - meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)
Synonym: Aminoacetic acid; Aminoethanoic acid; Glycocoll
CAS Number: 56-40-6
Empirical Formula (Hill Notation): C2H5NO2
Molecular Weight: 75.07
EC Number: 200-272-2
MDL Number: MFCD00008131
Linear Formula: NH2CH2COOH
Product Type: Chemical
| anion traces | chloride (Cl-): ≤50 mg/kg |
| sulfate (SO42-): ≤50 mg/kg | |
| assay | 99-101% (based on anhydrous substance) |
| color | white |
| form | crystalline powder |
| ign. residue | ≤0.1% (as SO4) |
| impurities | hydrolyzable substances, complies |
| organic volatile impurities, complies (GC) | |
| residual solvents, complies | |
| ≤0.001% heavy metals (as Pb) | |
| ≤1.0% ninhydrin-positive substances | |
| InChI | 1S/C2H5NO2/c3-1-2(4)5/h1, |
| InChI key | DHMQDGOQFOQNFH-UHFFFAOYSA |
| loss | ≤0.2% loss on drying, 105 °C, 2 h |
| mp | 240 °C (dec.) (lit.) |
| pH | 5.9-6.4 (20 °C, 5%) |
| pKa (25 °C) | (1) 2.35, (2) 9.60 |
| 2.35 | |
| quality | meets analytical specification of Ph. Eur., BP, USP |
| Quality Level | 200  |
| SMILES string | NCC(O)=O |
| solubility | alcohol: soluble 0.06 gm in 100 gm (Absolute) |
| alcohol: very slightly soluble | |
| diethyl ether: very slightly soluble | |
| H2O: soluble 25 gm in 100 ml at 25 degrees c | |
| H2O: soluble 39.1 gm in 100 ml at 50 degrees c | |
| pyridine: soluble 164 parts | |
| suitability | complies for appearance of solution |
| complies for reaction against H2SO4 | |
| in accordance for identity (IR) | |
| technique(s) | IR spectroscopy: suitable |
| Application: | Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes. It was used for biochemical and tolerance tests. |
| Biochem/physiol Actions: | Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS. During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria. It also increases the in vitro development of porcine blastocysts when used along with glucose. |
| Biochem/physiol Actions: | Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 99-101% (based on anhydrous substance) |
| mp | 240 °C (dec.) (lit.) |
| UNSPSC | 12352209 |