Urea
SIAL/15604 - puriss., meets analytical specification of Ph. Eur., BP, USP, 99.0-100.5%, 99.0-101.0% (calc. on dry substance)
Synonym: Carbamide; Carbonyldiamide
CAS Number: 57-13-6
Empirical Formula (Hill Notation): CH4N2O
Molecular Weight: 60.06
EC Number: 200-315-5
MDL Number: MFCD00008022
Linear Formula: NH2CONH2
Product Type: Chemical
anion traces | chloride (Cl-): ≤10 mg/kg |
sulfate (SO42-): ≤50 mg/kg | |
assay | 99.0-100.5% |
99.0-101.0% (calc. on dry substance) | |
cation traces | Fe: ≤0.5 mg/kg |
density | 1.335 g/mL at 25 °C (lit.) |
form | solid |
grade | puriss. |
ign. residue | ≤0.1% (as SO4) |
impurities | alkalic reac. substances, complies |
≤0.001% heavy metals (as Pb) | |
≤0.04% insoluble in ethanol | |
≤0.05% ammonium (NH4) | |
≤0.1% biuret(carbamylurea) | |
InChI | 1S/CH4N2O/c2-1(3)4/h(H4,2 |
InChI key | XSQUKJJJFZCRTK-UHFFFAOYSA |
loss | ≤1.0% loss on drying, 105 °C, 1 h |
mp | 132-135 °C |
132-135 °C (lit.) | |
quality | meets analytical specification of Ph. Eur., BP, USP |
Quality Level | 200 |
SMILES string | NC(N)=O |
solubility | H2O: soluble 480 g/L at 20 °C |
suitability | in accordance for appearance of solution |
in accordance for identity |
Application: | Urea has been used in the following studies: • Synthesis of SnO2 nanoparticles. • Synthesis of urethanes, ureides and semicarbazides. • Denaturation of protein isolated from Saccharomyces cerevisiae Y15696 strain • Protein electrophoretic studies. |
Application: | Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form. |
General description: | Urea is a colorless, odorless solid. It has prism-like crystals. It forms insoluble nitrate salts with nitric acid and oxalate salts with oxalic acid. On reaction with alkanes or substituted alkanes, it affords crystal-lattice inclusion compounds. Urea can be prepared from ammonia and carbon-dioxide, via Haber-Bosch process. It can also be used to prepare urea-formaldehyde resins, via condensation reaction. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 99.0-100.5%; 99.0-101.0% (calc. on dry substance) |
mp | 132-135 °C (lit.); 132-135 °C |
Density | 1.335 g/mL at 25 °C (lit.) |
UNSPSC | 12352100 |