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Pefabloc® SC

SIAL/15633 - certified reference material, TraceCERT®

Synonym: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride; AEBSF

CAS Number: 30827-99-7
Empirical Formula (Hill Notation): C8H10FNO2S · HCl
Molecular Weight: 239.69
MDL Number: MFCD00132962
Linear Formula: C8H10FNO2S · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-15633-50MG 50 mg
 $199.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 15633-50MG

 

application(s) forensics and toxicology
pharmaceutical (small molecule)
format neat
grade TraceCERT®
  certified reference material
InChI 1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H
InChI key WRDABNWSWOHGMS-UHFFFAOYSA-N
product line TraceCERT®
Quality Level 300 
shelf life limited shelf life, expiry date on the label
SMILES string FS(C1=CC=C(CCN)C=C1)(=O)=O.[H]Cl
storage temp. 2-8°C
technique(s) gas chromatography (GC): suitable
Application: Recommended concentrations for use are 0.1-1 mM.
Biochem/physiol Actions: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (AEBSF) is an irreversible serine protease inhibitor. Inhibition constants are similar to those of phenylmethanesulfonyl fluoride (PMSF) and diisopropylfluorophosphate (DFP). AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein, and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water, and improved stability in aqueous solutions. AEBSF can be used in cell culture in concentrations of up to 0.25 mM.
General description: This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
Legal Information: TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC
Legal Information: Pefabloc is a registered trademark of Pentapharm
Storage Temp. 2-8°C
UNSPSC 12352200

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