Enrofloxacin

SIAL/17849 - ≥99.0%

Synonym: Baytril

CAS Number: 93106-60-6
Empirical Formula (Hill Notation): C₁₉H₂₂FN₃O₃
Molecular Weight: 359.39
MDL Number: MFCD00792463
Linear Formula: C₁₉H₂₂FN₃O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-17849-5G-F	5 g	$161.00 1/EA		Add To Favorites
45-17849-25G-F	25 g	$619.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-negative bacteria
	Gram-positive bacteria
assay	≥99.0%
	99.0-101.0% (dried substance)
form	powder or crystals
InChI	1S/C19H22FN3O3/c1-2-21-5-7-22(8-6-21)17-10-16-13(9-15(17)20)18(24)14(19(25)26)11-23(16)12-3-4-12/h9-12H,2-8H2,1H3,(H,25,26)
InChI key	SPFYMRJSYKOXGV-UHFFFAOYSA-N
mode of action	DNA synthesis \| interferes
	enzyme \| inhibits
Quality Level	200
SMILES string	CCN1CCN(CC1)c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)C4CC4

Application:	Enrofloxacin has been used: • to investigate the pathological mechanisms resulting from the toxicity of fluoroquinolones in mammalian cells • to prepare a standard solution with 50% acetonitrile in a study to analyze illegal fish drugs used in aquaculture by employing surface-enhanced Raman spectroscopy (SERS) • as an analyte in a chemiluminescence reagent system
General description:	Chemical structure: fluoroquinolone
General description:	Enrofloxacin is a veterinary fluoroquinolone (FQ) antibiotic with broad-spectrum antimicrobial activity. FQ drugs chelate to iron with high affinity. This chelation leads to inhibition of Fe(II)-dependent dioxygenases involved in the regulation of epigenetic control, collagen maturation, and HIF (hypoxia-inducible factor) degradation. The side effects associated with FQ drugs are renal toxicity and tendinopathy. Enrofloxacin is used in aquaculture and its use may cause an increase in the growth of antibiotic resistant microbes in an aquatic environment. The drug may have negative effects on public health and environment.

Symbol	GHS07,GHS08
Signal word	Danger
Hazard statements	H302 - H317 - H334
Precautionary statements	P261 - P264 - P270 - P280 - P301 + P312 - P302 + P352
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

Purity	≥99.0%; 99.0-101.0% (dried substance)
UNSPSC	41116105

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