Butyric acid
SIAL/19215 - analytical standard
CAS Number: 107-92-6
Empirical Formula (Hill Notation): C4H8O2
Molecular Weight: 88.11
EC Number: 203-532-3
MDL Number: MFCD00002814
Linear Formula: CH3CH2CH2COOH
Product Type: Chemical
| application(s) | cleaning products cosmetics flavors and fragrances food and beverages personal care |
| assay | ≥99.5% (GC) |
| autoignition temp. | 824 °F |
| bp | 162 °C (lit.) |
| density | 0.964 g/mL at 25 °C (lit.) |
| expl. lim. | 10 % |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C4H8O2/c1-2-3-4(5)6/h2 |
| InChI key | FERIUCNNQQJTOY-UHFFFAOYSA |
| mp | −6-−3 °C (lit.) |
| Quality Level | 100  |
| refractive index | n |
| shelf life | limited shelf life, expiry date on the label |
| SMILES string | CCCC(O)=O |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor density | 3.04 (vs air) |
| vapor pressure | 0.43 mmHg ( 20 °C) |
| Application: | This analytical standard can also be used as follows: • Development and validation of a high-performance liquid chromatographic (HPLC) method combined with UV detection to determine four short-chain fatty acids— formic acid, acetic acid, propionic acid, and butyric acid, and lactic acid in bacterial culture samples after their liquid-liquid extraction (LLE) • Simultaneous analysis of 10 volatile and non-volatile organic acids in 18 samples of Korean traditional fermented soybean paste, doenjang, by HPLC combined with refractive index detector and gas chromatography coupled with flame ionization detector (GC-FID) • Determination of butyric, lactic, acetic, and propionic acids in sour cassava starch waste-water samples by reversed-phase high-performance liquid chromatography (HPLC) and capillary electrophoresis (CE), both coupled with diode array detection (DAD) • Multi-residue analysis of six short-chain fatty acids— acetic acid, propionic acid, butyric acid, isobutyric acid, valeric acid, and isovaleric acid, in biological samples of mice colon content by a gas chromatographic method combined with flame ionization detector (GC-FID) • Packed-fiber solid phase extraction (PFSPE) of eight short-chain fatty acids using polypyrrole nanofibers, from urine samples of children for quantification by gas chromatography-mass spectrometry (GC-MS) • Multi-residue analysis of 76 volatile compounds from jujube extract samples by gas chromatography-mass spectrometry (GC-MS) after their extraction by steam distillation combined with drop-by-drop extraction |
| General description: | Butyric acid is a four-carbon containing, saturated short-chain fatty acid. It commonly occurs in its ester form in animal-based fats and plant-based oils. It is a potent differentiation agent for cells and also possesses antiproliferative activity. In cultured mammalian cells, it affects growth rate, morphology, and gene expression. It also induces apoptosis. |
| General description: | This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here |
| Other Notes: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Recommended products: | Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
| Symbol |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302 - H314 |
| Precautionary statements | P270 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | C |
| Risk Statements | 22-34 |
| Safety Statements | 26-36-45 |
| RIDADR | UN 2820 8 / PGIII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 161.6 °F - closed cup |
| Flash Point(C) | 72 °C - closed cup |
| Purity | ≥99.5% (GC) |
| bp | 162 °C (lit.) |
| mp | −6-−3 °C (lit.) |
| Density | 0.964 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 85151701 |