Butyric acid
SIAL/19215 - analytical standard
CAS Number: 107-92-6
Empirical Formula (Hill Notation): C4H8O2
Molecular Weight: 88.11
EC Number: 203-532-3
MDL Number: MFCD00002814
Linear Formula: CH3CH2CH2COOH
Product Type: Chemical
| application(s) | cleaning products cosmetics flavors and fragrances food and beverages personal care |
| assay | ≥99.5% (GC) |
| autoignition temp. | 824 °F |
| bp | 162 °C (lit.) |
| density | 0.964 g/mL at 25 °C (lit.) |
| expl. lim. | 10 % |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C4H8O2/c1-2-3-4(5)6/h2 |
| InChI key | FERIUCNNQQJTOY-UHFFFAOYSA |
| mp | −6-−3 °C (lit.) |
| Quality Level | 100  |
| refractive index | n |
| shelf life | limited shelf life, expiry date on the label |
| SMILES string | CCCC(O)=O |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor density | 3.04 (vs air) |
| vapor pressure | 0.43 mmHg ( 20 °C) |
| Application: | This analytical standard can also be used as follows: • Development and validation of a high-performance liquid chromatographic (HPLC) method combined with UV detection to determine four short-chain fatty acids— formic acid, acetic acid, propionic acid, and butyric acid, and lactic acid in bacterial culture samples after their liquid-liquid extraction (LLE) • Simultaneous analysis of 10 volatile and non-volatile organic acids in 18 samples of Korean traditional fermented soybean paste, doenjang, by HPLC combined with refractive index detector and gas chromatography coupled with flame ionization detector (GC-FID) • Determination of butyric, lactic, acetic, and propionic acids in sour cassava starch waste-water samples by reversed-phase high-performance liquid chromatography (HPLC) and capillary electrophoresis (CE), both coupled with diode array detection (DAD) • Multi-residue analysis of six short-chain fatty acids— acetic acid, propionic acid, butyric acid, isobutyric acid, valeric acid, and isovaleric acid, in biological samples of mice colon content by a gas chromatographic method combined with flame ionization detector (GC-FID) • Packed-fiber solid phase extraction (PFSPE) of eight short-chain fatty acids using polypyrrole nanofibers, from urine samples of children for quantification by gas chromatography-mass spectrometry (GC-MS) • Multi-residue analysis of 76 volatile compounds from jujube extract samples by gas chromatography-mass spectrometry (GC-MS) after their extraction by steam distillation combined with drop-by-drop extraction |
| General description: | Butyric acid is a four-carbon containing, saturated short-chain fatty acid. It commonly occurs in its ester form in animal-based fats and plant-based oils. It is a potent differentiation agent for cells and also possesses antiproliferative activity. In cultured mammalian cells, it affects growth rate, morphology, and gene expression. It also induces apoptosis. |
| General description: | This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. |
| Other Notes: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Symbol |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302 - H314 |
| Precautionary statements | P270 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | C |
| Risk Statements | 22-34 |
| Safety Statements | 26-36-45 |
| RIDADR | UN 2820 8 / PGIII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 161.6 °F - closed cup |
| Flash Point(C) | 72 °C - closed cup |
| Purity | ≥99.5% (GC) |
| bp | 162 °C (lit.) |
| mp | −6-−3 °C (lit.) |
| Density | 0.964 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 85151701 |