Biotin
SIAL/19606 - tested according to Ph. Eur.
Synonym: Biotinum; D-Biotin; Bios II; Coenzyme R; Vitamin B7; Vitamin H
CAS Number: 58-85-5
Empirical Formula (Hill Notation): C10H16N2O3S
Molecular Weight: 244.31
EC Number: 200-399-3
MDL Number: MFCD00005541
Linear Formula: C10H16N2O3S
Product Type: Chemical
| agency | tested according to Ph. Eur. |
| application(s) | pharmaceutical (small molecule) |
| biological source | synthetic |
| InChI | 1S/C10H16N2O3S/c13-8(14)4 |
| InChI key | YBJHBAHKTGYVGT-ZKWXMUAHSA |
| mp | 231-233 °C (lit.) |
| Quality Level | 200  |
| SMILES string | [H][C@]12CS[C@@H](CCCCC(O |
| Application: | Biotin has been used for labeling the swine anti-rabbit IgG antibody and peroxidase. |
| Biochem/physiol Actions: | Biotin also referred to as vitamin H or vitamin B7 is a water-soluble B-vitamin that induces two to three fold increase in guanylate cyclase activity in rat liver, kidney, colon, cerebellum, and heart. It also stimulates the sperm motility and prolongs the survival of cryopreserved human spermatozoa. |
| Biochem/physiol Actions: | Biotin functions as an important cofactor for carboxylase enzymes in several metabolic pathways. It acts as a coenzyme in the metabolism of fatty acids, isoleucine and valine. Biotin is implicated in gluconeogenesis and citric acid cycle. It is involved in keratin synthesis and hence is used as a supplement for skin, hair and nail growth. Biotin promotes cell growth, production of fatty acids and the metabolism of fats and amino acids. It assists the transfer of carbon dioxide and also sustains a steady blood sugar level. |
| General description: | Biotin, also called vitamin B7 or vitamin H is a water-soluble B complex vitamin, which contains an uredo ring fused by a tetrahydrothiophene ring. It is found in several foods, like whole grains, nuts, legumes, unpolished rice and egg yolk. The normal gut flora also produces this vitamin. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 231-233 °C (lit.) |
| UNSPSC | 12352201 |