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Heparin sodium salt from porcine intestinal mucosa

SIAL/2106 - endotoxin, free

CAS Number: 9041-08-1
MDL Number: MFCD00081689
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-2106-10VL 10 vials
 $63.20
1/EA		 Add To Favorites
45-2106-15VL 15 vials
 $96.90
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biological source Porcine intestinal mucosa
color beige
compatibility for use with E-Toxate™
form powder
impurities endotoxin, free
InChI 1S/C26H42N2O37S5.Na/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36;/h5-20,23-26,28-29,31-
InChI key JRTRSJGZMRQDHI-UHFFFAOYSA-N
packaging preweighed vial of 300 USP units
Quality Level 200 
SMILES string [Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O
solubility acetone: insoluble
  alcohol: insoluble
  benzene: insoluble
  chloroform: insoluble
  diethyl ether: insoluble
  water: soluble 50 g/L
storage temp. room temp
usage sufficient for 5 mL blood anticoagulant
Application: Heparin sodium salt from porcine intestinal mucosa has been used as a M199 medium supplement used for maintaining human umbilical vein endothelial cells.
Biochem/physiol Actions: Heparin sodium salt is the salt form of heparinic acid and is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is an anticoagulant that produces its major anticoagulant effect by activating antithrombin. Heparin binds to antithrombin III, a naturally occurring plasma protease inhibitor and accelerates significantly the rate at which antithrombin III (AT-III) inhibits coagulation proteases (factor Xa and thrombin). Additionally, it also facilitates the stabilization and regulation of tryptase as an enzymatically active tetramer.
Disclaimer: Not for injection.
Legal Information: E-Toxate is a trademark of Sigma-Aldrich Co. LLC
Other Notes: To gain a comprehensive understanding of our extensive range of Polysaccharides  for your research, we encourage you to visit our Carbohydrates  Category page.
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. room temp
UNSPSC 12352201

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