Formamide
SIAL/221198 - ACS reagent, ≥99.5%
Synonym: Amide C1; Formic amide
CAS Number: 75-12-7
Empirical Formula (Hill Notation): CH3NO
Molecular Weight: 45.04
EC Number: 200-842-0
MDL Number: MFCD00007941
Linear Formula: HCONH2
Product Type: Chemical
| assay | ≥99.5% |
| autoignition temp. | 932 °F |
| bp | 210 °C (lit.) |
| color | APHA: ≤10 |
| density | 1.134 g/mL at 25 °C (lit.) |
| form | liquid |
| grade | ACS reagent |
| InChI | 1S/CH3NO/c2-1-3/h1H,(H2,2 |
| InChI key | ZHNUHDYFZUAESO-UHFFFAOYSA |
| mp | 2-3 °C (lit.) |
| pH | 4-10 (20 °C, 200 g/L) |
| Quality Level | 200 ![]() |
| refractive index | n |
| SMILES string | NC=O |
| technique(s) | PCR: suitable |
| transition temp | freezing point 2.0-3.0 °C |
| vapor density | 1.55 (vs air) |
| vapor pressure | 0.08 mmHg ( 20 °C) |
| 30 mmHg ( 129 °C) |
| Application: | Formamide destabilizes nucleic acid duplexes and may be used, typically, at a concentration of 50%, in hybridization protocols requiring lower hybridization temperatures. |
| Application: | The addition of formamide may enhance the specificity and efficiency of amplification of PCR (polymerase chain reaction). It may be used as an ammonia equivalent for the palladium-catalyzed aminocarbonylation of 1-bromo-3-trifluoromethyl |
| General description: | Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs. Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications. Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication. Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory. |
| Packaging: | 1, 4×4 L in glass bottle |
| Packaging: | 100, 500 mL in glass bottle |
| Symbol | GHS08 |
| Signal word | Danger |
| Hazard statements | H351 - H360D - H373 |
| Precautionary statements | P201 - P202 - P260 - P280 - P308 + P313 - P405 |
| Hazard Codes | T |
| Risk Statements | 61-40-48/22 |
| Safety Statements | 53-36/37-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 305.6 °F |
| Flash Point(C) | 152 °C |
| Purity | ≥99.5% |
| bp | 210 °C (lit.) |
| mp | 2-3 °C (lit.) |
| Density | 1.134 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352111 |


