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Brij® L4

SIAL/235989 - average Mn ~362

Synonym: Polyethylene glycol dodecyl ether; Polyoxyethylene (4) lauryl ether

CAS Number: 9002-92-0
MDL Number: MFCD00043063
Linear Formula: (C20H42O5)n
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-235989-5ML 5 mL
 $0.00
1/EA
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45-235989-100ML 100 mL
 $37.90
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45-235989-250ML 250 mL
 $70.50
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45-235989-1L 1 L
 $160.00
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density 0.95 g/mL at 25 °C (lit.)
description non-ionic
form solid or liquid
HLB 9
impurities ≤1% Water
InChI 1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3
InChI key WPMWEFXCIYCJSA-UHFFFAOYSA-N
mol wt average Mn ~362
mp 48 °C
Quality Level 200 
refractive index n20/D 1.451 (lit.)
SMILES string CCCCCCCCCCCCOCCOCCOCCOCCO
solubility water: insoluble
Application: Brij® L4 has been used:
• as a surfactant for the synthesis of copper(I) oxide (Cu2O) spherical nanoparticles using a microemulsion technique
• as a non-ionic surfactant for preparing reverse micelles to synthesize Pt3Co alloy nanoparticles
• as a surfactant to enhance the efficiency of interfacial coupling of hydrophobic materials and to make hydrogel
Biochem/physiol Actions: Brij® L4 exhibits amphiphilic properties. Brij L4 contains hydrophobic and hydrophilic regions that can form micelles and disperse hydrophobic drugs into the core of micelles. This in turn enhances drug solubility. Brij L4 also elicits a strong inhibitory effect against breast cancer resistance protein (BCRP) mediated drug efflux. It inhibits Taq adsorption better when compared to other commonly used surfactants. Brij L4 supports droplet polymerase chain reaction (PCR) in picoliter reaction volumes at standard Taq concentrations.
General description: Brij® L4 is a non-ionic surfactant. It comprises an alkyl (C12) tail attached to an oxyethylene headgroup.
Legal Information: Brij is a registered trademark of Croda International PLC
Packaging: 1 L in poly bottle
Packaging: 100, 250 mL in poly bottle
Packaging: 5 mL in glass bottle
mp 48 °C
Density 0.95 g/mL at 25 °C (lit.)
Refractive Index n20/D 1.451 (lit.)
UNSPSC 12161900

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