Potassium citrate tribasic monohydrate
SIAL/25107 - meets analytical specification of Ph. Eur., BP, FCC, E332, 99-100.5% (calc with ref. to anhyd. subst.)
Synonym: Citric acid tripotassium salt; Tripotassium citrate
CAS Number: 6100-05-6
Empirical Formula (Hill Notation): C6H5K3O7 · H2O
Molecular Weight: 324.41
EC Number: 231-905-0
MDL Number: MFCD00150442
Linear Formula: HOC(COOK)(CH2COOK)2 · H2O
Product Type: Chemical
| anion traces | chloride (Cl-): ≤30 mg/kg |
| oxalate (as oxalic acid): ≤100 mg/kg | |
| sulfate (SO42-): ≤50 mg/kg | |
| application(s) | pharmaceutical (small molecule) |
| assay | 99-100.5% (calc with ref. to anhyd. subst.) |
| cation traces | As: ≤1 mg/kg |
| Cu: ≤10 mg/kg | |
| Fe: ≤10 mg/kg | |
| Hg: ≤1 mg/kg | |
| Na: ≤3000 mg/kg | |
| Pb: ≤1 mg/kg | |
| Zn: ≤10 mg/kg | |
| form | powder or crystals |
| impurities | ≤0.0005% heavy metals (as Pb) |
| 4-6% water (Karl Fischer) | |
| InChI | 1S/C6H8O7.3K.H2O/c7-3(8)1 |
| InChI key | PJAHUDTUZRZBKM-UHFFFAOYSA |
| loss | 3-6 loss on drying, 180°C |
| mp | 275 °C (dec.) (lit.) |
| pH | 7-9 (20 °C, 5%) |
| quality | meets analytical specification of Ph. Eur., BP, FCC, E332 |
| Quality Level | 200  |
| SMILES string | O.[K+].[K+].[K+].OC(CC([O |
| solubility | alcohol: insoluble |
| glycerol: soluble 1 gm in 2.5 ml | |
| water: soluble 1 gm in 0.65 ml | |
| suitability | in accordance for appearance of solution |
| passes test for reaction against H2SO4 |
| Application: | Potassium citrate tribasic monohydrate has been used for preparing citrate-supplemented water for feeding the Car5A, Car5B, and DKO breeding pairs of mice. Citrate supplementation enhances the perinatal death in mice. It is a citrate-based salt used as a phase constituent for characterizing ionic-liquid-based aqueous biphasic systems (ABS) and as a buffering agent. |
| Biochem/physiol Actions: | Potassium citrate tribasic monohydrate is the potassium salt of citric acid. It enhances the bone density hence used in the treatment of osteoporosis. Additionally, it neutralizes the protein-induced metabolic acidosis. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 99-100.5% (calc with ref. to anhyd. subst.) |
| mp | 275 °C (dec.) (lit.) |
| UNSPSC | 12352300 |