1,2-Dimethoxyethane
SIAL/259527 - anhydrous, 99.5%, inhibitor-free
Synonym: DME; mono-Glyme; Dimethylglycol; Ethylene glycol dimethyl ether; Monoglyme
CAS Number: 110-71-4
Empirical Formula (Hill Notation): C4H10O2
Molecular Weight: 90.12
EC Number: 203-794-9
MDL Number: MFCD00008502
Linear Formula: CH3OCH2CH2OCH3
Product Type: Chemical
| assay | 99.5% |
| autoignition temp. | 396 °F |
| bp | 85 °C (lit.) |
| density | 0.867 g/mL at 25 °C (lit.) |
| evapn. residue | <0.0005% |
| expl. lim. | 10.4 % |
| form | liquid |
| grade | anhydrous |
| impurities | <0.003% water |
| <0.005% water (100 mL pkg) | |
| InChI | 1S/C4H10O2/c1-5-3-4-6-2/h |
| InChI key | XTHFKEDIFFGKHM-UHFFFAOYSA |
| mp | −58 °C (lit.) |
| pH | 7 |
| Quality Level | 100 ![]() |
| refractive index | n |
| SMILES string | COCCOC |
| vapor density | 3.1 (20 °C, vs air) |
| vapor pressure | 48 mmHg ( 20 °C) |
| Application: | 1,2-Dimethoxyethane may be used as a solvent in the following processes: • Synthesis of cyclic amines from amino alcohols via direct cyclodehydration. • Stereoselective synthesis of trans-1,2-disubstituted alkenes from 1-phenyl-1H-tetrazol-5-yl sulfones and aldehydes in the presence of potassium or sodium hexamethyldisilazide. • Synthesis of adamantylideneadamantane from 2-adamantanone via reductive coupling. |
| Packaging: | 1, 6×1, 2 L in Sure/Seal™ |
| Packaging: | 10 L in stainless steel drum |
| Packaging: | 100, 12×100 mL in Sure/Seal™ |
| Packaging: | 18 L in Pure-Pac™ 1 |
| Packaging: | View returnable container options . |
| Symbol | ![]() ![]() GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H315 - H332 - H360FD |
| Precautionary statements | P202 - P210 - P233 - P303 + P361 + P353 - P304 + P340 + P312 - P308 + P313 |
| Hazard Codes | F,T |
| Risk Statements | 60-61-11-19-38 |
| Safety Statements | 53-45 |
| RIDADR | UN 2252 3 / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 41.0 °F - closed cup |
| Flash Point(C) | 5 °C - closed cup |
| Supplemental Hazard Statements | EUH019 |
| Purity | 99.5% |
| bp | 85 °C (lit.) |
| mp | −58 °C (lit.) |
| Density | 0.867 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352112 |




