Acetonitrile
SIAL/271004 - anhydrous, 99.8%
Synonym: ACN; Cyanomethane; Ethyl nitrile; Methyl cyanide
CAS Number: 75-05-8
Empirical Formula (Hill Notation): C2H3N
Molecular Weight: 41.05
EC Number: 200-835-2
MDL Number: MFCD00001878
Linear Formula: CH3CN
Product Type: Chemical
Anhydrous, Sureseal
Anhydrous, Sureseal
Anhydrous, Sureseal
| assay | 99.8% |
| autoignition temp. | 973 °F |
| bp | 81-82 °C (lit.) |
| color | colorless |
| density | 0.786 g/mL at 25 °C (lit.) |
| evapn. residue | <0.0005% |
| expl. lim. | 16 % |
| form | liquid |
| grade | anhydrous |
| impurities | <0.001% water |
| <0.005% water (100 mL pkg) | |
| InChI | 1S/C2H3N/c1-2-3/h1H3 |
| InChI key | WEVYAHXRMPXWCK-UHFFFAOYSA |
| mp | −45 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | CC#N |
| solubility | water: soluble (completely) |
| technique(s) | solid phase extraction (SPE): suitable |
| vapor density | 1.41 (vs air) |
| vapor pressure | 72.8 mmHg ( 20 °C) |
| Application: | Acetonitrile may be used as a solvent to prepare: • 1,2-Azidoalcohols and 1,2-azidoamines via cerium(III) chloride assisted ring opening of epoxides and aziridines by sodium azide. • Cyano-bearing indolinones by oxidative arylalkylation of olefins in the presence of palladium catalyst. It may also be used as a reactant to synthesize: • Bis (diphenylphosphino) aceto • β-Acetamido ketones via coupling reaction with ketones or ketoesters and aldehydes in the presence of cobalt(II) chloride. |
| General description: | Acetonitrile, an aliphatic nitrile, is widely used as an organic solvent and intermediate in organic syntheses. It is transparent to UV-visible light, which makes it highly applicable in spectrophotometric and fluorimetric techniques. MeCN is utilized as a mobile phase component in many chromatographic techniques, due to its low viscosity, high elution strength and miscibility in water. It also plays a major role as an extractant medium in liquid-liquid extraction, solid-phase extraction or microextraction. |
| Packaging: | 1, 6×1, 2, 4×2 L in Sure/Seal™ |
| Packaging: | 100, 12×100 mL in Sure/Seal™ |
| Packaging: | 18 L in Pure-Pac™ 1 |
| Packaging: | 20, 50 L in Pure-Pac™ 2 |
| Packaging: | 200 L in Pure-Pac™ 1 |
| Packaging: | View returnable container options . |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H302 + H312 + H332 - H319 |
| Precautionary statements | P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-20/21/22-36 |
| Safety Statements | 16-36/37 |
| RIDADR | UN 1648 3 / PGII |
| WGK Germany | WGK 2 |
| Flash Point(F) | 35.6 °F - closed cup |
| Flash Point(C) | 2.0 °C - closed cup |
| Purity | 99.8% |
| bp | 81-82 °C (lit.) |
| mp | −45 °C (lit.) |
| Density | 0.786 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12191502 |