Chloroform
SIAL/288306 - anhydrous, ≥99%, contains 0.5-1.0% ethanol as stabilizer
Synonym: Methylidyne trichloride; Trichloromethane
CAS Number: 67-66-3
Empirical Formula (Hill Notation): CHCl3
Molecular Weight: 119.38
MDL Number: MFCD00000826
Linear Formula: CHCl3
Product Type: Chemical
| assay | ≥99% |
| bp | 60.5-61.5 °C (lit.) |
| color | colorless |
| contains | 0.5-1.0% ethanol as stabilizer |
| density | 1.48 g/mL at 25 °C |
| 1.492 g/mL at 25 °C (lit.) | |
| evapn. residue | <0.0003% |
| form | liquid |
| grade | anhydrous |
| impurities | <0.001% water |
| <0.005% water (100 mL pkg) | |
| InChI | 1S/CHCl3/c2-1(3)4/h1H |
| InChI key | HEDRZPFGACZZDS-UHFFFAOYSA |
| mp | −63 °C (lit.) |
| packaging | Sure/Seal™ of 1, 2 L |
| Sure/Seal™ of 100, 12x100 mL | |
| Quality Level | 100 ![]() |
| refractive index | n |
| SMILES string | ClC(Cl)Cl |
| vapor density | 4.1 (vs air) |
| vapor pressure | 160 mmHg ( 20 °C) |
| Application: | Chloroform has been used as a solvent for dissolving lipids and also as a cleansing agent. It may also be used in solvent extraction process and also for recrystallization. |
| General description: | Chloroform is a volatile chlorinated organic solvent whose vapors have a narcotic effect. Due to its light sensitivity, it may undergo degradation with time. This can be suppressed by adding ethanol as a stabilizer. The addition will increase the polarity of the solvent and potentially impact certain applications. |
| Legal Information: | Sure/Seal is a trademark of Sigma-Aldrich Co. LLC |
| Packaging: | 1, 2 L in Sure/Seal™ |
| Packaging: | 100, 12×100 mL in Sure/Seal™ |
| Symbol | ![]() GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 |
| Precautionary statements | P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 63-20/22-36/38-40-48/20/22 |
| Safety Statements | 26-36/37 |
| RIDADR | UN 1888 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | does not flash |
| Flash Point(C) | does not flash |
| Purity | ≥99% |
| bp | 60.5-61.5 °C (lit.) |
| mp | −63 °C (lit.) |
| Density | 1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12191502 |



