1,4-Dioxane
SIAL/296309 - anhydrous, 99.8%, contains <=25 ppm BHT as stabilizer
Synonym: Diethylene oxide; Dioxane
CAS Number: 123-91-1
Empirical Formula (Hill Notation): C4H8O2
Molecular Weight: 88.11
EC Number: 204-661-8
MDL Number: MFCD00006571
Linear Formula: C4H8O2
Product Type: Chemical
| assay | 99.8% |
| autoignition temp. | 356 °F |
| bp | 100-102 °C (lit.) |
| density | 1.034 g/mL at 25 °C (lit.) |
| evapn. residue | ≤0.005% |
| expl. lim. | 22 % |
| form | liquid |
| grade | anhydrous |
| impurities | <0.003% water |
| <0.005% water (100 mL pkg) | |
| InChI | 1S/C4H8O2/c1-2-6-4-3-5-1/ |
| InChI key | RYHBNJHYFVUHQT-UHFFFAOYSA |
| mp | 10-12 °C (lit.) |
| pH | 6.0-8 (20 °C, 500 g/L) |
| Quality Level | 200 ![]() |
| refractive index | n |
| SMILES string | C1COCCO1 |
| vapor density | 3 (vs air) |
| vapor pressure | 27 mmHg ( 20 °C) |
| 40 mmHg ( 25 °C) |
| Application: | 1,4-Dioxane may undergo nickel-catalyzed oxidative arylation with arylboronic acids to form α-arylated ethers. It may be used as a solvent to synthesize: • (Chloromethyl)dimethylphe • N-(2,2,2-trifluoro-1-hydroxyethyl)-acetamide from 2,2,2-trifluoro-1-methoxy |
| Other Notes: | The article number 296309-4X2L will be discontinued. Please order the single bottle 296309-2L which is physically identical with the same exact specifications. |
| Packaging: | 1, 6×1, 2 L in Sure/Seal™ |
| Packaging: | 100, 12×100 mL in Sure/Seal™ |
| Packaging: | 18 L in Pure-Pac™ 1 |
| Packaging: | 200 L in Kilo-Lab™ |
| Packaging: | 200 L in Pure-Pac™ 1 |
| Packaging: | View returnable container options . |
| Symbol | ![]() ![]() GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H319 - H335 - H351 |
| Precautionary statements | P202 - P210 - P233 - P240 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-19-36/37-40-66 |
| Safety Statements | 9-16-36/37-46 |
| RIDADR | UN1165 - class 3 - PG 2 - Dioxane |
| WGK Germany | WGK 2 |
| Flash Point(F) | 51.8 °F - closed cup |
| Flash Point(C) | 11 °C - closed cup |
| Supplemental Hazard Statements | EUH019 - EUH066 |
| Purity | 99.8% |
| bp | 100-102 °C (lit.) |
| mp | 10-12 °C (lit.) |
| Density | 1.034 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352005 |




