Ampicillin trihydrate

SIAL/31591 - VETRANAL^®, analytical standard

Synonym: D-(−)-α-Aminobenzylpenicillin

CAS Number: 7177-48-2
Empirical Formula (Hill Notation): C₁₆H₁₉N₃O₄S · 3H₂O
Molecular Weight: 403.45
EC Number: 200-709-7
MDL Number: MFCD00072036
Linear Formula: C₁₆H₁₉N₃O₄S · 3H₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-31591-250MG	250 mg	$55.80 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-negative bacteria
	Gram-positive bacteria
application(s)	clinical testing
color	white to off-white
format	neat
grade	analytical standard
InChI	1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1
InChI key	RXDALBZNGVATNY-CWLIKTDRSA-N
mode of action	cell wall synthesis \| interferes
mp	198-200 °C (dec.) (lit.)
product line	VETRANAL^®
Quality Level	100
shelf life	limited shelf life, expiry date on the label
SMILES string	O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O
storage temp.	2-8°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Application:	Ampicillin trihydrate has been used as reference standard for determining the residual solvents and its effect on ampicillin trihydrate crystal structure using GC, X-ray powder diffraction (XRPD) and Fourier transform infrared spectroscopy (FT-IR).
Application:	Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Application:	Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions:	A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
General description:	Ampicillin trihydrate is a stable hydrated form of ampicillin.
General description:	Chemical structure: ß-lactam
Legal Information:	VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes:	Keep container tightly closed in a dry and well-ventilated place.
Packaging:	250 mg

Symbol	GHS07,GHS08
Signal word	Danger
Hazard statements	H315 - H317 - H319 - H334 - H335
Precautionary statements	P261 - P264 - P280 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	36/37/38-42/43
Safety Statements	22-26-36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	198-200 °C (dec.) (lit.)
Storage Temp.	2-8°C
UNSPSC	41116107

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