Chlorpromazine hydrochloride
SIAL/31679 - VETRANAL®, analytical standard
Synonym: 2-
CAS Number: 69-09-0
Empirical Formula (Hill Notation): C17H19ClN2S · HCl
Molecular Weight: 355.33
EC Number: 200-701-3
MDL Number: MFCD00012654
Linear Formula: C17H19ClN2S · HCl
Product Type: Chemical
| application(s) | forensics and toxicology pharmaceutical (small molecule) |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C17H19ClN2S.ClH/c1-19( |
| InChI key | FBSMERQALIEGJT-UHFFFAOYSA |
| product line | VETRANAL® |
| Quality Level | 100  |
| shelf life | limited shelf life, expiry date on the label |
| SMILES string | Cl[H].CN(C)CCCN1c2ccccc2S |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | CPZ may have been used as standard for the determination of antipsychotic drug at a glassy carbon electrode using chemometric methods, such as classical least squares (CLS), principal component regression (PCR) and partial least squares (PLS). |
| Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Application: | Substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase. |
| Biochem/physiol Actions: | Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes. |
| Biochem/physiol Actions: | Phenothiazine antipsychotic; D2 dopamine receptor antagonist, H1 histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase. |
| General description: | Chlorpromazine hydrochloride (CPZ) is an antipsychotic drug which belongs to phenothiazine neuroleptic group. It is used in treating mental or personality disorders. |
| Legal Information: | VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 - H330 |
| Precautionary statements | P260 - P264 - P270 - P271 - P284 - P304 + P340 + P310 |
| Hazard Codes | T+ |
| Risk Statements | 25-26 |
| Safety Statements | 28-36/37-45 |
| RIDADR | UN 2811PIH 6.1 / PGI |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 41116107 |