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Chlorpromazine hydrochloride

SIAL/31679 - VETRANAL®, analytical standard

Synonym: 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride; CPZ; Largactil

CAS Number: 69-09-0
Empirical Formula (Hill Notation): C17H19ClN2S · HCl
Molecular Weight: 355.33
EC Number: 200-701-3
MDL Number: MFCD00012654
Linear Formula: C17H19ClN2S · HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-31679-250MG 250 mg
$68.00
1/EA
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application(s) forensics and toxicology
pharmaceutical (small molecule)
format neat
grade analytical standard
InChI 1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
InChI key FBSMERQALIEGJT-UHFFFAOYSA-N
product line VETRANAL®
Quality Level 100 
shelf life limited shelf life, expiry date on the label
SMILES string Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Application: CPZ may have been used as standard for the determination of antipsychotic drug at a glassy carbon electrode using chemometric methods, such as classical least squares (CLS), principal component regression (PCR) and partial least squares (PLS).
Application: Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Application: Substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase.
Biochem/physiol Actions: Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes.
Biochem/physiol Actions: Phenothiazine antipsychotic; D2 dopamine receptor antagonist, H1 histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase.
General description: Chlorpromazine hydrochloride (CPZ) is an antipsychotic drug which belongs to phenothiazine neuroleptic group. It is used in treating mental or personality disorders.
Legal Information: VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
UNSPSC 41116107

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