Meropenem trihydrate

SIAL/32460 - VETRANAL^®, analytical standard

Synonym: (1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate

CAS Number: 119478-56-7
Empirical Formula (Hill Notation): C₁₇H₂₅N₃O₅S · 3H₂O
Molecular Weight: 437.51
MDL Number: MFCD08600005
Linear Formula: C₁₇H₂₅N₃O₅S · 3H₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-32460-25MG	25 mg	$144.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 32460-25MG

Properties
Descriptions
Safety Info.
Basic Data

application(s)	forensics and toxicology pharmaceutical (small molecule)
format	neat
grade	analytical standard
InChI	1S/C17H25N3O5S.3H2O/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4;;;/h7-12,18,21H,5-6H2,1-4H3,(H,24,25);3*1H2/t7-,8-,9+,10+,11-,12-;;;/m1.../s1
InChI key	CTUAQTBUVLKNDJ-OBZXMJSBSA-N
product line	VETRANAL^®
Quality Level	100
shelf life	limited shelf life, expiry date on the label
shipped in	wet ice
SMILES string	O.O.O.C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)=C(N2C1=O)C(O)=O
storage temp.	−20°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Application:	Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions:	Meropenem has been used as a reference standard in an experiment conducted to investigate the effects on in vivo efficacy caused due to chemical differences in three generic products of meropenem.
Biochem/physiol Actions:	Meropenem penetrates cell walls and binds to penicillin-binding protein targets. It acts against aerobes and anaerobes including E. coli, Klebsiella, Clostridium, Enterococcus sp. It is a common cause of mild transient aminotransferase elevations and can rarely result in clinically apparent, cholestatic liver injury.
Biochem/physiol Actions:	Meropenem trihydrate is an ultra-broad spectrum beta-lactam antibiotic active against both Gram-positive and Gram-negative bacteria.
General description:	Meropenem trihydrate (Meropenem) is a broad-spectrum carbapenem with antibacterial properties. It inhibits cell wall synthesis in both gram-negative and gram-positive bacteria.
Legal Information:	VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319
Precautionary statements	P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	41116107

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