Voriconazole

SIAL/32483 - VETRANAL^®, analytical standard

Synonym: 2R,3S-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol; UK-109496

CAS Number: 137234-62-9
Empirical Formula (Hill Notation): C₁₆H₁₄F₃N₅O
Molecular Weight: 349.31
MDL Number: MFCD00905717
Linear Formula: C₁₆H₁₄F₃N₅O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-32483-25MG	25 mg	$145.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 32483-25MG

Properties
Descriptions
Safety Info.
Basic Data

application(s)	forensics and toxicology pharmaceutical (small molecule)
format	neat
grade	analytical standard
InChI	1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1
InChI key	BCEHBSKCWLPMDN-MGPLVRAMSA-N
product line	VETRANAL^®
Quality Level	100
shelf life	limited shelf life, expiry date on the label
SMILES string	C[C@@H](c1ncncc1F)[C@](O)(Cn2cncn2)c3ccc(F)cc3F
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Application:	Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions:	It has been used as one of the constituent of YPD (1% yeast extract, 2% peptone, 2% glucose) liquid media.
Biochem/physiol Actions:	Voriconazole is an antifungal used to treat serious fungal infections. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.
Biochem/physiol Actions:	Voriconazole is an antifungal used to treat serious fungal infections. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-a sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.
General description:	Voriconazole is a second-generation triazole, and is derived from fluconazole. It has a broad and enhanced antifungal spectrum as compared to other older triazoles. It is mostly well tolerated and is available in both oral and intravenous formulations.
Legal Information:	VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Symbol	GHS06,GHS08
Signal word	Danger
Hazard statements	H301 - H341 - H351 - H361 - H371 - H372 - H373 - H412
Precautionary statements	P202 - P260 - P264 - P270 - P273 - P301 + P310
Hazard Codes	T
Risk Statements	61-25-40-48/22-52/53
Safety Statements	53-22-36/37-45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

UNSPSC

41116107

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