Voriconazole
SIAL/32483 - VETRANAL®, analytical standard
Synonym: 2R,3S-
CAS Number: 137234-62-9
Empirical Formula (Hill Notation): C16H14F3N5O
Molecular Weight: 349.31
MDL Number: MFCD00905717
Linear Formula: C16H14F3N5O
Product Type: Chemical
application(s) | forensics and toxicology pharmaceutical (small molecule) |
format | neat |
grade | analytical standard |
InChI | 1S/C16H14F3N5O/c1-10(15-1 |
InChI key | BCEHBSKCWLPMDN-MGPLVRAMSA |
product line | VETRANAL® |
Quality Level | 100 ![]() |
shelf life | limited shelf life, expiry date on the label |
SMILES string | C[C@@H](c1ncncc1F)[C@](O) |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
Biochem/physiol Actions: | It has been used as one of the constituent of YPD (1% yeast extract, 2% peptone, 2% glucose) liquid media. |
Biochem/physiol Actions: | Voriconazole is an antifungal used to treat serious fungal infections. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes. |
Biochem/physiol Actions: | Voriconazole is an antifungal used to treat serious fungal infections. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-a sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes. |
General description: | Voriconazole is a second-generation triazole, and is derived from fluconazole. It has a broad and enhanced antifungal spectrum as compared to other older triazoles. It is mostly well tolerated and is available in both oral and intravenous formulations. |
Legal Information: | VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH |
Symbol | ![]() ![]() |
Signal word | Danger |
Hazard statements | H301 - H341 - H351 - H361 - H371 - H372 - H373 - H412 |
Precautionary statements | P202 - P260 - P264 - P270 - P273 - P301 + P310 |
Hazard Codes | T |
Risk Statements | 61-25-40-48/22-52/53 |
Safety Statements | 53-22-36/37-45 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
UNSPSC | 41116107 |