Glycine
SIAL/33226 - puriss. p.a., reag. Ph. Eur., buffer substance, 99.7-101% (calc. to the dried substance)
Synonym: Aminoacetic acid; Aminoethanoic acid; Glycocoll
CAS Number: 56-40-6
Empirical Formula (Hill Notation): C2H5NO2
Molecular Weight: 75.07
EC Number: 200-272-2
MDL Number: MFCD00008131
Linear Formula: NH2CH2COOH
Product Type: Chemical
| agency | reag. Ph. Eur. |
| USP/NF | |
| anion traces | chloride (Cl-): ≤30 mg/kg |
| sulfate (SO42-): ≤20 mg/kg | |
| assay | 99.7-101% (calc. to the dried substance) |
| cation traces | Fe: ≤5 mg/kg |
| form | crystalline powder |
| functional group | amine |
| carboxylic acid | |
| grade | puriss. p.a. |
| ign. residue | ≤0.05% (as SO4) |
| impurities | ≤0.001% heavy metals (as Pb) |
| ≤0.02% ammonium (NH4) | |
| ≤0.1% water (Karl Fischer) | |
| ≤1.0% ninhydrin-positive substances | |
| InChI | 1S/C2H5NO2/c3-1-2(4)5/h1, |
| InChI key | DHMQDGOQFOQNFH-UHFFFAOYSA |
| loss | ≤0.5% loss on drying, 105°C, 2 h |
| mp | 240 °C (dec.) (lit.) |
| pH | 5.9-6.4 (20 °C, 5%) |
| pKa (25 °C) | (1) 2.35, (2) 9.60 |
| 2.35 | |
| Quality Level | 200 ![]() |
| SMILES string | NCC(O)=O |
| suitability | in accordance for identity (IR) |
| technique(s) | IR spectroscopy: suitable |
| Application: | Glycine can be used as:• A reactant in the natural soil clay-catalyzed cleavage and polycondensation with pyrogallol. • A catalyst in the Knoevenagel reaction between aryl aldehydes and malononitrile to form a C=C bond. • A reagent in the metal-free synthesis of biaryls from aryl sulfoxides and sulfonanilides via sigmatropic rearrangement. |
| Biochem/physiol Actions: | Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 99.7-101% (calc. to the dried substance) |
| mp | 240 °C (dec.) (lit.) |
| UNSPSC | 12352209 |

