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Clotrimazole

SIAL/33894 - VETRANAL®, analytical standard

Synonym: 1-(o-Chloro-α,α-diphenylbenzyl)imidazole; 1-(o-Chlorotrityl)imidazole; 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole

CAS Number: 23593-75-1
Empirical Formula (Hill Notation): C22H17ClN2
Molecular Weight: 344.84
EC Number: 245-764-8
MDL Number: MFCD00057220
Linear Formula: C22H17ClN2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-33894-100MG-R 100 mg
$0.00
1/EA
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antibiotic activity spectrum fungi
application(s) agriculture
environmental
format neat
grade analytical standard
InChI 1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
InChI key VNFPBHJOKIVQEB-UHFFFAOYSA-N
mode of action protein synthesis | interferes
product line VETRANAL®
Quality Level 100 
shelf life limited shelf life, expiry date on the label
SMILES string Clc1ccccc1C(c2ccccc2)(c3ccccc3)n4ccnc4
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Application: Clotrimazole may be used as a reference standard for the determination of the analyte in topical creams and ear drops by reversed-phase high-performance liquid chromatographic (RP-HPLC) method.
Application: Clotrimazole may be used as an analytical reference standard for the determination of the analyte in:
• Milk samples using solid-phase extraction followed by high-performance liquid chromatography (SPE-HPLC).
• Environmental water samples using dispersive liquid-liquid microextraction followed by high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS).

Application: Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description: Clotrimazole, a non-toxic, systemic, imidazole derivative with broad-spectrum antimycotic activity, is primarily used in the treatment of oropharyngeal candidiasis.
General description: Its mode of action involves the inhibition of ergosterol synthesis, which leads to structural and functional damage of the cell membrane.
Legal Information: VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH
UNSPSC 41116107

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