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Norfloxacin

SIAL/33899 - VETRANAL®, analytical standard

Synonym: 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid

CAS Number: 70458-96-7
Empirical Formula (Hill Notation): C16H18FN3O3
Molecular Weight: 319.33
EC Number: 274-614-4
MDL Number: MFCD00079532
Linear Formula: C16H18FN3O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-33899-100MG-R 100 mg
 $148.00
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agency EPA 1694
application(s) clinical testing
format neat
grade analytical standard
InChI 1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChI key OGJPXUAPXNRGGI-UHFFFAOYSA-N
product line VETRANAL®
Quality Level 100 
shelf life limited shelf life, expiry date on the label
SMILES string CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3
storage temp. 2-8°C
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Application: Norfloxacin may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations, biological fluids and sewage using various chromatography techniques.
Application: Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions: Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).
Mode of action: inhibits bacterial DNA replication
Antimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria
General description: Norfloxacin is an antimicrobial drug, belonging to the class of fluoroquinolones (FQs), which shows broad-spectrum activity against a wide range of Gram-negative and Gram-positive organisms.
Legal Information: VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Temp. 2-8°C
UNSPSC 41116107

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