Glutaraldehyde solution
SIAL/340855 - 50 wt. % in H2O
Synonym: Glutaric dialdehyde solution; Pentane-1,5-dial
CAS Number: 111-30-8
Empirical Formula (Hill Notation): C5H8O2
Molecular Weight: 100.12
MDL Number: MFCD00007025
Linear Formula: OHC(CH2)3CHO
Product Type: Chemical
application(s) | cell analysis genomic analysis life science and biopharma sample preparation |
color | colorless |
concentration | 50 wt. % in H2O |
density | 1.106 g/mL at 25 °C |
form | liquid |
InChI | 1S/C5H8O2/c6-4-2-1-3-5-7/ |
InChI key | SXRSQZLOMIGNAQ-UHFFFAOYSA |
mp | -21 °C ((-6 °F)) |
Quality Level | 200 |
refractive index | n |
SMILES string | [H]C(CCCC([H])=O)=O |
solubility | water: soluble |
suitability | suitable for microfluidics/nanofluidic |
technique(s) | electron microscopy: suitable |
immunoblotting: suitable | |
immunohistochemistry: suitable | |
vapor density | 1.05 (vs air) |
vapor pressure | 15 mmHg ( 20 °C) |
Application: | Cross-linking agent for gelatin, poly(vinyl alcohol), and polyheptapeptides. |
Application: | Glutaraldehyde may be used in the following studies: • To compose the fixative solution (Glutaraldehyde + Paraformaldehyde + NaPO4) for use in high-resolution light microscopy and electron microscopy studies. • To study the conjugation of goat anti-horseradish peroxidase with alkaline phosphatase by a reported method. • To compose the primary fixative, which is employed to protect the deterioration of cytoplasmic features of yeast cells during permanganate fixation. |
Features and Benefits: | • Versatile and adaptable for wide variety of research applications • Ready-made solution reduces the need for preparation time |
General description: | Glutaraldehyde (Glutaric dialdehyde, Pentane-1,5-dial) is an aliphatic dialdehyde that can be employed as an effective biochemical reagent for various purposes such as a protein crosslinker, enzyme immobilization in microscopy, histochemistry, and cytochemistry. It serves as an amine-reactive homobifunctional crosslinker and a cell fixative before SDS-PAGE, staining, or electron microscopy, making it suitable for a wide range of morphological studies. Glutaraldehyde is capable of efficiently crosslinking amine and hydrazine derivatives to proteins and other amine-containing polymers. Notably, in certain reactions, biotin hydrazides have been directly coupled to nucleic acids using glutaraldehyde, presenting a potential utility in conjugating fluorescent hydrazides and hydroxylamines to DNA. In histology studies, Glutaraldehyde is also employed to preserve tissue sections and prepare them for closer examination. |
Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
Other Notes: | To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page. |
Packaging: | 1, 3 L in glass bottle |
Packaging: | 25 mL in glass bottle |
Symbol | GHS05,GHS06,GHS08,GHS09 |
Signal word | Danger |
Hazard statements | H302 - H314 - H317 - H331 - H334 - H335 - H410 |
Precautionary statements | P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
Hazard Codes | T,N |
Risk Statements | 23/25-34-42/43-50 |
Safety Statements | 26-36/37/39-45-61 |
RIDADR | UN2922 - class 8 - PG 2 - EHS - acidic - Corrosive liquids, toxi |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Supplemental Hazard Statements | EUH071 |
mp | -21 °C ((-6 °F)) |
Density | 1.106 g/mL at 25 °C |
Refractive Index | n |
UNSPSC | 12352114 |