Fosfomycin sodium
SIAL/34089 - VETRANAL®, analytical standard
Synonym: Phosphomycin disodium salt; (−)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid; Fosfomycin; Phosphonomycin
Empirical Formula (Hill Notation): C3H5Na2O4P
Molecular Weight: 182.02
EC Number: 247-409-2
MDL Number: MFCD22741288
Linear Formula: C3H5Na2O4P
Product Type: Chemical
application(s) | clinical testing |
format | neat |
grade | analytical standard |
InChI | 1S/C3H7O4P.2Na/c1-2-3(7-2 |
InChI key | QZIQJIKUVJMTDG-JSTPYPERSA |
product line | VETRANAL® |
Quality Level | 100 ![]() |
shelf life | limited shelf life, expiry date on the label |
SMILES string | [Na+].[Na+].C[C@@H]1O[C@@ |
storage temp. | 2-8°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
Biochem/physiol Actions: | Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited. |
Legal Information: | VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |