Fosfomycin sodium
SIAL/34089 - VETRANAL®, analytical standard
Synonym: Phosphomycin disodium salt; (−)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid; Fosfomycin; Phosphonomycin
Empirical Formula (Hill Notation): C3H5Na2O4P
Molecular Weight: 182.02
EC Number: 247-409-2
MDL Number: MFCD22741288
Linear Formula: C3H5Na2O4P
Product Type: Chemical
application(s) | clinical testing |
format | neat |
grade | analytical standard |
InChI | 1S/C3H7O4P.2Na/c1-2-3(7-2 |
InChI key | QZIQJIKUVJMTDG-JSTPYPERSA |
product line | VETRANAL® |
Quality Level | 100 |
shelf life | limited shelf life, expiry date on the label |
SMILES string | [Na+].[Na+].C[C@@H]1O[C@@ |
storage temp. | 2-8°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
Biochem/physiol Actions: | Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited. |
Legal Information: | VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany |
Recommended products: | Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |