DCC
SIAL/36650 - puriss., ≥99.0% (GC)
Synonym: N,N′-Dicyclohexylcarbodiimide
CAS Number: 538-75-0
Empirical Formula (Hill Notation): C13H22N2
Molecular Weight: 206.33
EC Number: 208-704-1
MDL Number: MFCD00011659
Linear Formula: C6H11N=C=NC6H11
Product Type: Chemical
application(s) | peptide synthesis |
assay | ≥99.0% (GC) |
bp | 122-124 °C/6 mmHg (lit.) |
form | solid |
grade | puriss. |
InChI | 1S/C13H22N2/c1-3-7-12(8-4 |
InChI key | QOSSAOTZNIDXMA-UHFFFAOYSA |
mp | 32.0-37.0 °C |
34-35 °C (lit.) | |
Quality Level | 200 ![]() |
reaction suitability | reaction type: Coupling Reactions |
SMILES string | C1CCC(CC1)N=C=NC2CCCCC2 |
solubility | methylene chloride: 0.1 g/mL, clear, colorless |
Application: | DCC may be used to promote the esterification of 7-((tert-butyldimethylsilyl)oxy)h It may be also used to synthesize: • 1,3-Thiazetedine derivatives via [2+2] cycloaddition with 2-phenylethenyl- and 2-(4-nitrophenyl)ethenyl isothiocyanates. • 1,3,5-Oxadiazine-4-thio • Sterically hindered 1,3,4-oxadiazole derivatives by reacting with (N-isocyanimino)triphenylph |
General description: | DCC is an organic compound widely used as a coupling reagent in peptide synthesis. It is also employed as an efficient dehydrating agent for the preparation of amides, esters, nitriles, and anhydrides. Alcohols can be converted into aldehydes and ketone by Moffatt oxidation reaction in the presence of DCC and dimethyl sulfoxide (DMSO). |
Other Notes: | Coupling reagent, reagent for dehydrations etc. Modifies bovine heart mitochondrial transhydrogenase; Inhibition of F1F0-ATPase and other proton-translocating enzymes |
Packaging: | 100, 500 g in poly bottle |
Packaging: | 2.5 kg in poly bottle |
Symbol | ![]() ![]() |
Signal word | Danger |
Hazard statements | H302 - H311 - H317 - H318 |
Precautionary statements | P280 - P301 + P312 + P330 - P302 + P352 + P312 - P305 + P351 + P338 + P310 |
Hazard Codes | T |
Risk Statements | 22-24-41-43 |
Safety Statements | 24-26-37/39-45 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | 235.4 °F - closed cup |
Flash Point(C) | 113 °C - closed cup |
Purity | ≥99.0% (GC) |
bp | 122-124 °C/6 mmHg (lit.) |
mp | 32.0-37.0 °C; 34-35 °C (lit.) |
UNSPSC | 12352000 |