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Potassium antimonyl tartrate trihydrate

SIAL/383376 - ACS reagent, ≥99%

Synonym: Antimony potassium tartrate trihydrate; Tartar emetic

CAS Number: 28300-74-5
Empirical Formula (Hill Notation): C8H4K2O12Sb2 · 3H2O
Molecular Weight: 667.87
EC Number: 234-293-3
MDL Number: MFCD00167056
Linear Formula: C8H4K2O12Sb2 · 3H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-383376-100G 100 g
 $91.90
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This image depicts SKU: 383376-100G

 

assay ≥99%
  99.0-103.0%
cation traces As: ≤0.015%
form powder
grade ACS reagent
impurities ≤0.020 meq/g Titr. acid or base
InChI 1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4
InChI key WBTCZEPSIIFINA-UHFFFAOYSA-J
loss ≤2.7% loss on drying
mp ≥300 °C (lit.)
Quality Level 200 
SMILES string O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O
solubility water: soluble
Application: Potassium antimonyl tartrate trihydrate has been used in the dose-inhibition experiments to evaluate the dose-inhibition curves of antimony-based antileishmanial compounds against Leishmania promastigotes in medium 199.
Application: Potassium antimonyl tartrate trihydrate may be used to prepare antimony (Sb(III)) stock solution in deionized water (100mg/L). It may also be employed in the spectrophotometric determination of total phosphorus in dry sediments.
General description: Potassium antimonyl tartrate trihydrate is a metalloid salt in which the antimony is in trivalent state (SbIII). Potassium antimonyl tartrate (PAT) is an antiparasitic agent predominantly used for treating infections caused by the parasite Leishmania. Its antiangiogenic and antitumor properties has been investigated in nonsmall-cell lung cancer (NSCLC) cells. Studies in Chinese hamster ovary cells show that it may prevent the repair of DNA double strand breaks (DSBs) caused by γ-irradiation.
Packaging: 100 g in poly bottle
Purity ≥99%; 99.0-103.0%
mp ≥300 °C (lit.)
UNSPSC 12352100

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