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3-(Dimethylamino)-1-propylamine

SIAL/39380 - purum, ≥98.0% (GC)

Synonym: N,N-Dimethyl-1,3-diaminopropane; N,N-Dimethyl-1,3-propanediamine

CAS Number: 109-55-7
Empirical Formula (Hill Notation): C5H14N2
Molecular Weight: 102.18
EC Number: 203-680-9
MDL Number: MFCD00008216
Linear Formula: (CH3)2N(CH2)3NH2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-39380-250ML 250 mL
$47.70
1/EA
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45-39380-1L 1 L
$57.20
1/EA
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assay ≥98.0% (GC)
bp 133 °C (lit.)
density 0.812 g/mL at 25 °C (lit.)
form liquid
grade purum
impurities ≤2% water
InChI 1S/C5H14N2/c1-7(2)5-3-4-6/h3-6H2,1-2H3
InChI key IUNMPGNGSSIWFP-UHFFFAOYSA-N
Quality Level 200 
refractive index n20/D 1.435 (lit.)
  n20/D 1.436
SMILES string CN(C)CCCN
vapor density 3.6 (vs air)
vapor pressure 5 mmHg ( 20 °C)
Application: 3-(Dimethylamino)-1-propylamine (DMAPA) is suitable reagent used in the following studies:
• As a cationic moiety to form the ionic liquid, 3-(dimethylamino)-1-propylaminium formate ([DMAPA]FA) which is a potential reagent to extract protein from yeast cells.
• As an aminating agent in the palladium-catalyzed amination of aryl amines.
• In the derivatization of pullulan to form cationic pullulan.
• In the partial modification of poly(styrene-alt-maleic anhydride) to form N-substituted maleimide.
• As a test compound in the parallel synthesis of alkylamine lipidoids.
• To cleave the polyamides synthesized by solid phase methods on Boc-β-Ala-PAM resin.
It may be used in the following studies:
• Synthesis of (N,N-dialkylamino)alkyl-2-amino benzamide by reacting with isatoic anhydride.
• As a reagent for the anomeric deacetylation of protected sugars.
• Preparation of bioreducible copolymers used in gene delivery.
General description: 3-(Dimethylamino)-1-propylamine (DMAPA, N,N-dimethyl-1,3-propanediamine) is a dialkylamino alkyl amine. It has been prepared from dimethylamine and acrylonitrile and confirmed by 1H NMR. It participates in the synthesis of bio-based zwitterionic surfactants from waste cooking oil (WCO).
Other Notes: Industrial applications
Purity ≥98.0% (GC)
bp 133 °C (lit.)
Density 0.812 g/mL at 25 °C (lit.)
Refractive Index n20/D 1.435 (lit.); n20/D 1.436
UNSPSC 12352100

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