α-Cyano-4-hydroxycinnamic acid
SIAL/39468 - suitable for matrix substance for MALDI-MS, Ultra pure
Synonym: α-CCA; α-CHCA; α-Cyano; 4-HCCA; ACCA
CAS Number: 28166-41-8
Empirical Formula (Hill Notation): C10H7NO3
Molecular Weight: 189.17
EC Number: 248-879-1
MDL Number: MFCD00004204
Linear Formula: HOC6H4CH=C(CN)CO2H
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 39468-10MG-KC-F
| analyte chemical class(es) | glycans, peptides, proteins |
| cation traces | Al: ≤1 mg/kg |
| Ba: ≤1 mg/kg | |
| Ca: ≤1 mg/kg | |
| Cd: ≤1 mg/kg | |
| Co: ≤1 mg/kg | |
| Cr: ≤1 mg/kg | |
| Cu: ≤1 mg/kg | |
| Fe: ≤1 mg/kg | |
| K: ≤1 mg/kg | |
| Li: ≤1 mg/kg | |
| Mg: ≤1 mg/kg | |
| Mn: ≤1 mg/kg | |
| Na: ≤1 mg/kg | |
| Ni: ≤1 mg/kg | |
| Pb: ≤1 mg/kg | |
| Sr: ≤1 mg/kg | |
| Zn: ≤1 mg/kg | |
| form | solid |
| InChI | 1S/C10H7NO3/c11-6-8(10(13 |
| InChI key | AFVLVVWMAFSXCK-VMPITWQZSA |
| mp | 245-250 °C |
| 245-250 °C (lit.) | |
| Quality Level | 100  |
| SMILES string | OC(=O)C(=Cc1ccc(O)cc1)C |
| solubility | methanol: 10 mg/mL, clear |
| storage temp. | 2-8°C |
| suitability | suitable for matrix substance for MALDI-MS |
| technique(s) | MALDI-MS: suitable |
| Application: | It was used as matrix in improving the detection of low concentration protein digests on MALDI-TOF. |
| General description: | α-Cyano-4-hydroxycinnamic acid (α-CHCA) functions as matrix and helps in facilitating ionization of proteins and peptides in a matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometer. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H317 - H319 - H335 |
| Precautionary statements | P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 245-250 °C (lit.); 245-250 °C |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116105 |