Tetrahydrofuran
SIAL/401757 - anhydrous, ≥99.9%, inhibitor-free
Synonym: THF; Butylene oxide; Oxolane; Tetramethylene oxide
CAS Number: 109-99-9
Empirical Formula (Hill Notation): C4H8O
Molecular Weight: 72.11
EC Number: 203-726-8
MDL Number: MFCD00005356
Linear Formula: C4H8O
Product Type: Chemical
Anhydrous, Sureseal
Anhydrous, Sureseal
| assay | ≥99.9% |
| autoignition temp. | 610 °F |
| bp | 65-67 °C (lit.) |
| density | 0.889 g/mL at 25 °C (lit.) |
| evapn. residue | <0.0005% |
| expl. lim. | 1.8-11.8 % |
| form | liquid |
| grade | anhydrous |
| impurities | ≤20 ppm peroxide (as H2O2) |
| <0.002% water | |
| <0.005% water (100 mL pkg) | |
| InChI | 1S/C4H8O/c1-2-4-5-3-1/h1- |
| InChI key | WYURNTSHIVDZCO-UHFFFAOYSA |
| mp | −108 °C (lit.) |
| pH | ~7 |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | C1CCOC1 |
| solubility | H2O: soluble |
| vapor density | 2.5 (vs air) |
| vapor pressure | 114 mmHg ( 15 °C) |
| 143 mmHg ( 20 °C) |
| Application: | Tetrahydrofuran was used as a solvent in the formation of diacetylinic polymers. It may be used in the following processes: • Formation of butyrolactone (BTL) by green oxidation method. • Aqueous THF solution to modify the polystyrene surface by swelling process. • As a solvent for lignin depolymerization to isolate phenolic monomer. |
| General description: | Tetrahydrofuran (THF) is a saturated cyclic ether with a potential use as a biofuel. Its combustion studies have been investigated. Reports suggest that it is a better promoter than 1,3 dioxolane for CO2-hydrate formation. |
| Legal Information: | Pure-Pac is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Other Notes: | "Greener alternatives are available for many THF applications, 2-Methyltetrahydrofuran (673277) and Cyclopentyl methyl ether (791962) Read more about THF alternatives: 2-Methyltetrahydroun (2-MeTHF): A biomass-Derived solvent with Broad Applications in Organic Chemistry  The toxicological assessment of cyclopentyl methyl ether (CPME) as a green solvent " |
| Other Notes: | Pure-Pac® II containers require the Micromatic MacroValve coupler for dispensing solvents, Z560723. |
| Packaging: | 1, 6×1, 2, 4×2 L in Sure/Seal™ |
| Packaging: | 100, 12×100 mL in Sure/Seal™ |
| Packaging: | 18 L in Pure-Pac™ 1 |
| Packaging: | 20, 50 L in Pure-Pac™ 2 |
| Packaging: | 200 L in Pure-Pac™ 2 |
| Packaging: | 56 L in Pure-Pac™ 1 |
| Packaging: | 90 L in Kilo-Lab™ |
| Packaging: | View returnable container options . |
| Symbol |    GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H302 - H319 - H335 - H336 - H351 |
| Precautionary statements | P201 - P202 - P210 - P301 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-19-36/37-40 |
| Safety Statements | 13-16-29-33-36-37-46 |
| RIDADR | UN 2056 3 / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | -6.2 °F - closed cup |
| Flash Point(C) | -21.2 °C - closed cup |
| Supplemental Hazard Statements | EUH019 |
| Purity | ≥99.9% |
| bp | 65-67 °C (lit.) |
| mp | −108 °C (lit.) |
| Density | 0.889 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12191501 |