Cyanocobalamin

SIAL/43107 - tested according to Ph. Eur.

Synonym: Vitamin B₁₂; α-(5,6-Dimethylbenzimidazolyl)cyanocobamide; CN-Cbl; Cyanocob(III)alamin; Cyanocobalamin

CAS Number: 68-19-9
Empirical Formula (Hill Notation): C₆₃H₈₈CoN₁₄O₁₄P
Molecular Weight: 1355.37
EC Number: 200-680-0
Linear Formula: C₆₃H₈₈CoN₁₄O₁₄P
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-43107-10G-F	10 g	$1460.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	tested according to Ph. Eur.
	USP/NF
application(s)	cell analysis
assay	96.0-102.0% dry basis
biological source	fermentation/recombinant
color	dark red
form	powder
InChI	1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57?,59-,60+,61+,62+;;/m1../s1
InChI key	RMRCNWBMXRMIRW-QJRSUKKJSA-L
Quality Level	100
SMILES string	C/C(C1=N[C@]([C@]([C@H](CC(N)=O)[C@@]/2(C)CCC(NC[C@@H](OP([O-])(O[C@H]3[C@@H](O)[C@@H](N4C=[N]5C6=C4C=C(C)C(C)=C6)O[C@@H]3CO)=O)C)=O)([H])N([Co+]5C#N)C2=C(C)/C([C@@H](CCC(N)=O)C/7(C)C)=NC7=C/8)(C)[C@@](C)(CC(N)=O)[C@@H]1CCC(N)=O)=C9N=C8[C@@H](CCC(N)=O)[C@
solubility	acetone: insoluble
	alcohol: soluble
	chloroform: insoluble
	diethyl ether: insoluble
	water: soluble 1 gm in 80 ml
storage temp.	2-8°C

Application:	Cyanocobalamin was added in the assay buffer during the analysis step of ELISA for ensuring that all transcobalamin was saturated with cobalamin before analysis. Cyanocobalamin was also used for examining its impact on the expression of mPer1 and mPer2 in vivo.
Biochem/physiol Actions:	Cyanocobalamin plays a role in functioning of brain and nervous system. It is also involved in hematopoiesis. Vitamin B₁₂ deficiency leads to megaloblastic anemia. It is also associated with irreversible nervous system breakdown leading to spinal cord degeneration.
Biochem/physiol Actions:	Cyanocobalamin refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. Cyanocobalamin along with other B vitamins thiamine (B1) and pyridoxine (B6) blocks the thermal hyperalgesia in rats with neuropathic pain caused by spinal ganglia compression (CCD) or loose ligation of the sciatic nerve (CCI). It can stimulate the anaerobic biodegradation of chloroform.
General description:	Cyanocobalamin, also referred to as Vitamin B₁₂, is a water soluble vitamin.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

Purity	96.0-102.0% dry basis
Storage Temp.	2-8°C
UNSPSC	12352200

To Order From a Quote