Sodium dodecyl sulfate
SIAL/436143 - ACS reagent, ≥99.0%
Synonym: Dodecyl sodium sulfate; Dodecyl sulfate sodium salt; Lauryl sulfate sodium salt; SDS; Sodium lauryl sulfate
CAS Number: 151-21-3
Empirical Formula (Hill Notation): C12H25NaO4S
Molecular Weight: 288.38
EC Number: 205-788-1
MDL Number: MFCD00036175
Linear Formula: CH3(CH2)11OSO3Na
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: 436143-100G
This image depicts SKU: 436143-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: 436143-25G
This image depicts SKU: 436143-25G
| λ | 3 %H2O reference |
| assay | ≥99.0% |
| cation traces | heavy metals (as Pb): ≤0.002% |
| description | 62 |
| anionic | |
| form | solid |
| grade | ACS reagent |
| HLB | 40 |
| impurities | ≤0.06 meq/g Titr. Base |
| ≥96.0% fatty alcohols | |
| <4.0% unsulfated alcohols | |
| InChI | 1S/C12H26O4S.Na/c1-2-3-4- |
| InChI key | DBMJMQXJHONAFJ-UHFFFAOYSA |
| loss | ≤1.0% loss on drying |
| mol wt | 288.38 g/mol |
| mp | 204-207 °C (lit.) |
| Quality Level | 200  |
| SMILES string | [Na+].CCCCCCCCCCCCOS([O-] |
| solubility | H2O: soluble 1 gm in 10 ml (opalescent solution) |
| UV absorption | λ: 220-350 nm Amax: ≤0.1 |
| Application: | Anionic detergent |
| Application: | Sodium dodecyl sulfate was used as a test compound for studying that whether Bacillus amyloliquefaciens KPS46 can induce priming, signaling, protein production as well as systemic protection in soybean (Glycine max L.) against several diseases. |
| Biochem/physiol Actions: | Sodium dodecyl sulfate (SDS) is an anionic detergent that can form complexes with protein through hydrophobic interactions. Studies have reported that the hydrodynamic functions of protein-SDS complexes are governed by the length of their polypeptide chains. Thus, SDS-based electrophoretic techniques can separate protein molecules based on their molecular weights. Additionally, SDS can solubilize cell membranes and can extract membrane-bound proteins. |
| Features and Benefits: | • Highly versatile surfactant for your molecular biology and biochemical research • Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications |
| General description: | Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate, is a versatile anionic surfactant with a broad range of applications in cell biology, biochemistry, and various industries. Its amphiphilic nature, characterized by a hydrophobic hydrocarbon tail and a hydrophilic sulfate head group, makes it an effective detergent capable of solubilizing and denaturing proteins, lipids, and other hydrophobic molecules. In protein biochemistry, SDS plays a pivotal role in protein extraction and SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis). Its ability to denature proteins by disrupting their secondary and tertiary structures allows for their uniform migration through a polyacrylamide gel matrix based on their molecular weight. This technique, SDS-PAGE, has become an indispensable tool for analyzing protein size and purity. Beyond protein analysis, SDS also finds applications in nucleic acid extraction and hybridization techniques. Its detergent properties aid in the lysis of cells and the solubilization of cellular components, facilitating the extraction of DNA and RNA. This makes SDS a valuable reagent in various molecular biology protocols, including PCR (polymerase chain reaction) and Southern blotting. Sodium dodecyl sulfate stands as a versatile and widely used surfactant with a diverse range of applications due to its ability to solubilize, denature, and separate biological molecules for cell biology and biochemical research. |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Packaging: | 25, 100 g in poly bottle |
| Symbol |    GHS02,GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H228 - H302 + H332 - H315 - H318 - H335 - H412 |
| Precautionary statements | P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-21/22-37/38-41 |
| Safety Statements | 26-36/37-39 |
| RIDADR | UN1325 - class 4.1 - PG 3 - Flammable solids, organic, n.o.s., H |
| WGK Germany | WGK 2 |
| Flash Point(F) | 338.0 °F |
| Flash Point(C) | 170 °C |
| Purity | ≥99.0% |
| mp | 204-207 °C (lit.) |
| UNSPSC | 12161900 |