N,N-Dimethylformamide
SIAL/437573 - ACS reagent, ≥99.8%
Synonym: DMF; NSC 5356
CAS Number: 68-12-2
Empirical Formula (Hill Notation): C3H7NO
Molecular Weight: 73.09
EC Number: 200-679-5
MDL Number: MFCD00003284
Linear Formula: HCON(CH3)2
Product Type: Chemical
| assay | ≥99.8% |
| autoignition temp. | 833 °F |
| bp | 153 °C (lit.) |
| color | APHA: ≤15 |
| density | 0.944 g/mL (lit.) |
| evapn. residue | ≤0.005% |
| expl. lim. | 15.2 % |
| form | liquid |
| grade | ACS reagent |
| impurities | ≤0.0005 meq/g Titr. acid |
| ≤0.003 meq/g Titr. base | |
| ≤0.15% water | |
| InChI | 1S/C3H7NO/c1-4(2)3-5/h3H, |
| InChI key | ZMXDDKWLCZADIW-UHFFFAOYSA |
| mp | −61 °C (lit.) |
| pH | 6.7 |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | [H]C(=O)N(C)C |
| solubility | water: miscible |
| technique(s) | electrophoresis: suitable |
| vapor density | 2.5 (vs air) |
| vapor pressure | 2.7 mmHg ( 20 °C) |
| Application: | N,N-Dimethylformamide (DMF) may be used in the following processes: • As a solvent synthesis of gold nanoparticles. • As a solvent in capillary electrophoresis. • Regioselective synthesis of N,N-dimethylaminopyridzines by reacting with choropyridazines. • Synthesis of urea-N,N-dimethylformamide, a 3:1 solvate with urea. |
| Application: | Solvent for many hydrophobic organic compounds. |
| General description: | N,N-Dimethylformamide (DMF) is a polar organic solvent with a wide range of industrial applications. It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation. Along with phosphorus oxychloride, it forms Vilsmeier reagent used in the formylation of reactive aromatic and heteroaromatic substrates. Dielectric relaxation experiments on DMF have been conducted between 238.15K and 338.15K. The thermophysical properties of the molecular interactions between DMF and the ionic liquids, ammonium salts and imidazolium salts have been studied. The characteristics of solute-solvent interactions between ammonium nitrate and DMF have been investigated. |
| General description: | Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs. Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications. Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication. Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory. |
| Packaging: | 18 L in VerSA-Flow™ |
| Packaging: | 4×4 L in PVC-coated bottle |
| Symbol |    GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H226 - H312 + H332 - H319 - H360D |
| Precautionary statements | P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 61-20/21-36 |
| Safety Statements | 53-45 |
| RIDADR | UN 2265 3 / PGIII |
| WGK Germany | WGK 2 |
| Flash Point(F) | 135.5 °F - closed cup |
| Flash Point(C) | 57.5 °C - closed cup |
| Purity | ≥99.8% |
| bp | 153 °C (lit.) |
| mp | −61 °C (lit.) |
| Density | 0.944 g/mL (lit.) |
| Refractive Index | n |
| UNSPSC | 12352111 |