Chloroform
SIAL/437581 - ACS reagent, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer
Synonym: Methylidyne trichloride; Trichloromethane
CAS Number: 67-66-3
Empirical Formula (Hill Notation): CHCl3
Molecular Weight: 119.38
MDL Number: MFCD00000826
Linear Formula: CHCl3
Product Type: Chemical
| assay | ≥99.8% |
| bp | 60.5-61.5 °C |
| 60.5-61.5 °C (lit.) | |
| cation traces | Pb: ≤0.05 ppm |
| color | APHA: ≤10 |
| contains | 0.5-1.0% ethanol as stabilizer |
| density | 1.492 g/mL at 25 °C (lit.) |
| dilution | (for analytical testing) |
| evapn. residue | ≤0.001% |
| form | liquid |
| grade | ACS reagent |
| InChI | 1S/CHCl3/c2-1(3)4/h1H |
| InChI key | HEDRZPFGACZZDS-UHFFFAOYSA |
| mp | −63 °C (lit.) |
| packaging | PVC-coated bottle of 4x4 L |
| Quality Level | 200 ![]() |
| refractive index | n |
| SMILES string | ClC(Cl)Cl |
| vapor density | 4.1 (vs air) |
| vapor pressure | 160 mmHg ( 20 °C) |
| Application: | Chloroform may be used in the following processes: • Synthesis of colloidal hydrophobic CdSe core nanocrystals (quantum dots). • Preparing phospholipid solutions. • As a solvent in the photolysis reaction of ruthenium complexes. • Solvent for recrystallization. • As a reference compound to detect the presence of chloroform in tobacco smokes. • As an extractant in solvent extraction process. |
| General description: | Chloroform is a colorless, volatile chlorinated organic solvent whose vapors have narcotic effect. It is susceptible to degradation with time which can be suppressed by adding ethanol as a stabilizer. Since ethanol is added in higher concentration it leads to increase in polarity which may have a potential influence on some of the applications. |
| General description: | Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs. Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications. Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication. Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory. |
| Packaging: | 4×4 L in PVC-coated bottle |
| Symbol | ![]() GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 |
| Precautionary statements | P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 63-20/22-36/38-40-48/20/22 |
| Safety Statements | 26-36/37 |
| RIDADR | UN 1888 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | does not flash |
| Flash Point(C) | does not flash |
| Purity | ≥99.8% |
| bp | 60.5-61.5 °C (lit.); 60.5-61.5 °C |
| mp | −63 °C (lit.) |
| Density | 1.492 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352101 |



