Tetrahydrofuran
SIAL/439215 - suitable for HPLC, ≥99.9%, inhibitor-free
Synonym: THF; Butylene oxide; Oxolane; Tetramethylene oxide
CAS Number: 109-99-9
Empirical Formula (Hill Notation): C4H8O
Molecular Weight: 72.11
EC Number: 203-726-8
MDL Number: MFCD00005356
Linear Formula: C4H8O
Product Type: Chemical
| λ | H2O reference |
| assay | ≥99.9% |
| autoignition temp. | 610 °F |
| bp | 65-67 °C (lit.) |
| density | 0.889 g/mL at 25 °C (lit.) |
| evapn. residue | <0.0005% |
| expl. lim. | 1.8-11.8 % |
| form | liquid |
| grade | HPLC grade |
| impurities | ≤0.015% peroxide (as H2O2) |
| <0.02% water | |
| InChI | 1S/C4H8O/c1-2-4-5-3-1/h1- |
| InChI key | WYURNTSHIVDZCO-UHFFFAOYSA |
| mp | −108 °C (lit.) |
| Quality Level | 100  |
| refractive index | n |
| SMILES string | C1CCOC1 |
| solubility | H2O: soluble |
| technique(s) | HPLC: suitable |
| UV absorption | λ: 212 nm Amax: 1.0 |
| λ: 250 nm Amax: 0.180 | |
| λ: 300 nm Amax: 0.020 | |
| λ: 350-400 nm Amax: 0.005 | |
| vapor density | 2.5 (vs air) |
| vapor pressure | 114 mmHg ( 15 °C) |
| 143 mmHg ( 20 °C) |
| Application: | Tetrahydrofuran may be used as a solvent in the following processes: • Formation of diacetylinic polymers. • RAFT polymerization of p-acetoxystyrene. • Synthesis of di-tert-butyl-Phosphinoferrocene. It may be used in the following processes: • As mobile phase solvent in high-performance liquid chromatography. • As a solvent in the preparation of spin-coated poly(bisphenol A decane ether). • Formation of butyrolactone (BTL) by green oxidation method. • As a solvent for lignin depolymerization to isolate phenolic monomer. |
| General description: | Tetrahydrofuran (THF) is a saturated cyclic ether with a potential use as a biofuel. Its combustion studies have been reported. Reports suggest it is a better promoter than 1,3 dioxolane for CO2-hydrate formation. The effect of THF on the biological systems has been studied. |
| Other Notes: | Discover LiChropur reagents ideal for HPLC or LC-MS analysis |
| Packaging: | 4×4 L in PVC-coated bottle |
| Symbol |    GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H302 - H319 - H335 - H336 - H351 |
| Precautionary statements | P201 - P202 - P210 - P301 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-19-36/37-40 |
| Safety Statements | 13-16-29-33-36-37-46 |
| RIDADR | UN 2056 3 / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | -6.2 °F - closed cup |
| Flash Point(C) | -21.2 °C - closed cup |
| Supplemental Hazard Statements | EUH019 |
| Purity | ≥99.9% |
| bp | 65-67 °C (lit.) |
| mp | −108 °C (lit.) |
| Density | 0.889 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12190000 |