Erythromycin A hydrate
SIAL/46256 - VETRANAL®, analytical standard
CAS Number: 207291-29-0
Empirical Formula (Hill Notation): C37H67NO13 · xH2O
Molecular Weight: 733.93 (anhydrous basis)
EC Number: 204-040-1
Linear Formula: C37H67NO13 · xH2O
Product Type: Chemical
| application(s) | clinical testing |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C37H67NO13.2H2O/c1-14- |
| InChI key | IWGQNYZQLVGGCS-ZKSNWDMWSA |
| product line | VETRANAL® |
| Quality Level | 200  |
| shelf life | limited shelf life, expiry date on the label |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains. |
| Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Biochem/physiol Actions: | Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site. Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria. |
| Caution: | This product is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C. |
| Legal Information: | VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Preparation Note: | This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 41116107 |