Novobiocin sodium salt

SIAL/46531 - VETRANAL^®, analytical standard

CAS Number: 1476-53-5
Empirical Formula (Hill Notation): C₃₁H₃₅N₂NaO₁₁
Molecular Weight: 634.61
EC Number: 216-023-6
Linear Formula: C₃₁H₃₅N₂NaO₁₁
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-46531-250MG	250 mg	$101.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-positive bacteria
application(s)	clinical testing
assay	97.9% (HPLC)
format	neat
grade	analytical standard
InChI	1S/C31H35N2O11.Na/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29;/h7,9-13,23,25-26,29,34,36H,8H2,1-6H3,(H2,32,39)(H,33,37);/q-1;+1
InChI key	AXOUUAINTJNFRS-UHFFFAOYSA-N
mode of action	DNA synthesis \| interferes
	enzyme \| inhibits
product line	VETRANAL^®
Quality Level	100
shelf life	limited shelf life, expiry date on the label
SMILES string	[Na+].CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3C([O-])=C(NC(=O)c4ccc(O)c(CC=C(C)C)c4)C(=O)Oc3c2C)OC1(C)C
storage temp.	2-8°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Application:	For the production of positively supercoiled plasmid DNA. Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Inhibitor of retrovirus RNA-dependent DNA-polymerase.
Application:	Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions:	Mode of Action: Inhibits DNA synthesis by inhibiting the enzyme Topoisomerase II. Antimicrobial spectrum: Gram-positive bacterial.
General description:	Chemical structure: coumarin-glycoside
Legal Information:	VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 - H317 - H319
Precautionary statements	P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36-43
Safety Statements	26-36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	97.9% (HPLC)
Storage Temp.	2-8°C
UNSPSC	41116107

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