Synonym: 1,3,5(10)-Estratriene-3,17α-diol; 3,17α-Dihydroxy-1,3,5(10)-estratriene; Epiestradiol
CAS Number: 57-91-0
Empirical Formula (Hill Notation): C18H24O2
Molecular Weight: 272.38
EC Number: 200-354-8
MDL Number: MFCD00064144
Linear Formula: C18H24O2
Product Type: Chemical
| application(s) |
pharmaceutical (small molecule) |
| format |
neat |
| grade |
analytical standard |
| impurities |
≤2.0% water |
| InChI |
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1 |
| InChI key |
VOXZDWNPVJITMN-SFFUCWETSA-N |
| optical activity |
[α]/D 52.0 to 56.0°, c = 1 in ethanol |
| product line |
VETRANAL® |
| Quality Level |
200  |
| shelf life |
limited shelf life, expiry date on the label |
| SMILES string |
[H][C@]12CC[C@]3(C)[C@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(O)ccc24 |
| technique(s) |
gas chromatography (GC): suitable |
| |
HPLC: suitable |
| Application: |
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Biochem/physiol Actions: |
Estradiol (known as alpha Estradiol or 17 alpha Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture.17-estradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke. |
| Legal Information: |
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany |
GHS08,GHS09