Penicillin G potassium salt
SIAL/46609 - VETRANAL®, analytical standard
Synonym: Benzylpenicillin potassium salt
CAS Number: 113-98-4
Empirical Formula (Hill Notation): C16H17KN2O4S
Molecular Weight: 372.48
EC Number: 204-038-0
MDL Number: MFCD00036193
Linear Formula: C16H17KN2O4S
Product Type: Chemical
agency | EPA 1694 |
antibiotic activity spectrum | Gram-positive bacteria |
application(s) | cleaning products clinical cosmetics environmental food and beverages forensics and toxicology personal care pharmaceutical (small molecule) |
format | neat |
grade | analytical standard |
InChI | 1S/C16H18N2O4S.K/c1-16(2) |
InChI key | IYNDLOXRXUOGIU-LQDWTQKMSA |
mode of action | cell wall synthesis | interferes |
product line | VETRANAL® |
Quality Level | 100 |
shelf life | limited shelf life, expiry date on the label |
SMILES string | [K+].[H][C@]12SC(C)(C)[C@ |
storage temp. | 2-8°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Application: | Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans. |
Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
Biochem/physiol Actions: | Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking. Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria. |
Caution: | Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL. |
General description: | Chemical structure: ß-lactam |
Legal Information: | VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H317 |
Precautionary statements | P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364 |
Hazard Codes | Xn |
Risk Statements | 42/43 |
Safety Statements | 36/37 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |