Formaldehyde solution
SIAL/47673 - tested according to Ph. Eur.
Synonym: Formaldehydi solutio 35 per centum; Formalin
CAS Number: 50-00-0
Empirical Formula (Hill Notation): CH2O
Molecular Weight: 30.03
MDL Number: MFCD00003274
Linear Formula: HCHO
Product Type: Chemical
agency | tested according to Ph. Eur. |
USP/NF | |
autoignition temp. | 572 °F |
concentration | 25-50% |
contains | 9.0-15.0 % (v/v) methanol as stabilizer |
density | 1.09 g/mL at 25 °C (lit.) |
form | liquid |
InChI | 1S/CH2O/c1-2/h1H2 |
InChI key | WSFSSNUMVMOOMR-UHFFFAOYSA |
Quality Level | 200 |
SMILES string | [H]C([H])=O |
solubility | water: soluble |
suitability | suitable for manufacturing use (Laboratory chemicals) |
vapor density | 1.03 (vs air) |
vapor pressure | 52 mmHg ( 37 °C) |
Application: | Formaldehyde solution has been used to fix labeled cells during flow cytometry. |
Biochem/physiol Actions: | Formaldehyde is the simplest aldehyde that denatures the bihelical regions of RNA and converts the polynucleotides into random coils. It is a genotoxic substance that significantly induces DNA-protein crosslinks (DPC), sister-chromatid exchanges, micronuclei formation and leads to cytotoxicity. It also induces tumors in the nasal epithelium of rats and supposed to be a human carcinogen. |
Caution: | may become turbid on storage |
Symbol | GHS02,GHS05,GHS06,GHS08 |
Signal word | Danger |
Hazard statements | H226 - H301 + H311 - H314 - H317 - H330 - H335 - H341 - H350 - H370 |
Precautionary statements | P201 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
Hazard Codes | T |
Risk Statements | 45-23/24/25-34-39/23/24/25-43-68 |
Safety Statements | 53-26-36/37/39-45 |
RIDADR | UN 2209 8 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | 133.0 °F - closed cup |
Flash Point(C) | 56.11 °C - closed cup |
Density | 1.09 g/mL at 25 °C (lit.) |
UNSPSC | 12352114 |