1,1,1,3,3,3-Hexafluoro-2-propanol
SIAL/52517 - for GC derivatization, LiChropur™, ≥99.8%
Synonym: HFP; Hexafluoroisopropanol
CAS Number: 920-66-1
Empirical Formula (Hill Notation): C3H2F6O
Molecular Weight: 168.04
EC Number: 213-059-4
MDL Number: MFCD00011651
Linear Formula: (CF3)2CHOH
Product Type: Chemical
assay | ≥99.8% |
≥99.8% (GC) | |
bp | 59 °C (lit.) |
density | 1.596 g/mL at 25 °C (lit.) |
grade | for GC derivatization |
InChI | 1S/C3H2F6O/c4-2(5,6)1(10) |
InChI key | BYEAHWXPCBROCE-UHFFFAOYSA |
mp | −4 °C (lit.) |
quality | LiChropur™ |
Quality Level | 100 ![]() |
reaction suitability | reagent type: derivatization reagent reaction type: Acylations |
reagent type: derivatization reagent reaction type: Esterifications |
|
refractive index | n |
SMILES string | OC(C(F)(F)F)C(F)(F)F |
technique(s) | gas chromatography (GC): suitable |
Application: | Suitable for the derivatization of glutamic acid, homovanillic, iso-homovanillic and dihydroxyphenyl acetic acids and Υ-aminobutyric acid. |
General description: | Hexafluoroisopropanol (HFP) is generally used to denature the native state of proteins, and it also stabilizes the a-helical conformation in unfolded peptides and proteins like ß-lactoglobulin and melittin. |
Legal Information: | LiChropur is a trademark of Merck KGaA, Darmstadt, Germany |
Other Notes: | Reagent for hexafluoroisopropyl ester, N-pentafluoropropionyl, and trifluoroacetyl.. |
Other Notes: | Size-exclusion chromatography in 1,1,1,3,3,3-hexafluoro-2- |
Symbol | ![]() ![]() |
Signal word | Danger |
Hazard statements | H314 - H361fd - H373 |
Precautionary statements | P201 - P202 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
Hazard Codes | C |
Risk Statements | 63-22-34-62 |
Safety Statements | 26-36/37/39-45 |
RIDADR | UN 3265 8 / PGII |
WGK Germany | WGK 2 |
Flash Point(F) | closed cup - boils before flash |
Flash Point(C) | closed cup - boils before flash |
Purity | ≥99.8% (GC); ≥99.8% |
bp | 59 °C (lit.) |
mp | −4 °C (lit.) |
Density | 1.596 g/mL at 25 °C (lit.) |
Refractive Index | n |
UNSPSC | 12352104 |