Spermine
SIAL/55513 - analytical standard
Synonym: N,N′-Bis(3-aminopropyl)-1,4-diaminobutane; Gerontine; Musculamine; Neuridine
CAS Number: 71-44-3
Empirical Formula (Hill Notation): C10H26N4
Molecular Weight: 202.34
EC Number: 200-754-2
MDL Number: MFCD00008215
Linear Formula: NH2(CH2)3NH(CH2)4NH(CH2)3NH2
Product Type: Chemical
application(s) | cleaning products cosmetics food and beverages personal care |
assay | ≥99.0% (GC) |
97.0-103.0% (T) | |
bp | 150 °C/5 mmHg (lit.) |
format | neat |
grade | analytical standard |
impurities | ≤0.5% carbonate |
≤0.5% spermidine | |
InChI | 1S/C10H26N4/c11-5-3-9-13- |
InChI key | PFNFFQXMRSDOHW-UHFFFAOYSA |
mp | 28-30 (lit.) |
Quality Level | 100 ![]() |
shelf life | limited shelf life, expiry date on the label |
SMILES string | [H]N(CCCN)CCCCN([H])CCCN |
storage temp. | 2-8°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
Biochem/physiol Actions: | Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS). |
Hazard Codes | C |
Risk Statements | 34 |
Safety Statements | 26-36/37/39-45 |
RIDADR | UN 3259PSN2 8 / PGII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99.0% (GC); 97.0-103.0% (T) |
bp | 150 °C/5 mmHg (lit.) |
mp | 28-30 (lit.) |
Storage Temp. | 2-8°C |
UNSPSC | 85151701 |