Caffeine
SIAL/56396 - certified reference material, TraceCERT®
Synonym: 1,3,7-
CAS Number: 58-08-2
Empirical Formula (Hill Notation): C8H10N4O2
Molecular Weight: 194.19
EC Number: 200-362-1
MDL Number: MFCD00005758
Linear Formula: C8H10N4O2
Product Type: Chemical
application(s) | cleaning products cosmetics flavors and fragrances food and beverages personal care |
format | neat |
grade | TraceCERT® |
certified reference material | |
InChI | 1S/C8H10N4O2/c1-10-4-9-6- |
InChI key | RYYVLZVUVIJVGH-UHFFFAOYSA |
mp | 234-236.5 °C (lit.) |
product line | TraceCERT® |
Quality Level | 300 ![]() |
SMILES string | CN1C(=O)N(C)c2ncn(C)c2C1= |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
Biochem/physiol Actions: | A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms. |
General description: | Caffeine is a behaviorally active substance mainly found in beverages like coffee and tea. It can have diverse effects on brain functions. |
General description: | This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ. Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate. Download your certificate at: http://www.sigma-aldrich. |
Legal Information: | TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC |
Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P301 + P312 + P330 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 234-236.5 °C (lit.) |
UNSPSC | 12352210 |