Imidazole
SIAL/56750 - puriss. p.a., ≥99.5% (GC)
Synonym: 1,3-
CAS Number: 288-32-4
Empirical Formula (Hill Notation): C3H4N2
Molecular Weight: 68.08
EC Number: 206-019-2
MDL Number: MFCD00005183
Linear Formula: C3H4N2
Product Type: Chemical
anion traces | chloride (Cl-): ≤50 mg/kg |
sulfate (SO42-): ≤50 mg/kg | |
assay | ≥99.5% (GC) |
bp | 256 °C (lit.) |
cation traces | Ca: ≤10 mg/kg |
Cd: ≤5 mg/kg | |
Co: ≤5 mg/kg | |
Cr: ≤5 mg/kg | |
Cu: ≤5 mg/kg | |
Fe: ≤5 mg/kg | |
K: ≤50 mg/kg | |
Mg: ≤5 mg/kg | |
Mn: ≤5 mg/kg | |
Na: ≤50 mg/kg | |
Ni: ≤5 mg/kg | |
Pb: ≤5 mg/kg | |
Zn: ≤5 mg/kg | |
form | flakes |
powder or crystals | |
grade | puriss. p.a. |
ign. residue (900 °C) | ≤0.1% |
InChI | 1S/C3H4N2/c1-2-5-3-4-1/h1 |
InChI key | RAXXELZNTBOGNW-UHFFFAOYSA |
mp | 88-91 °C |
88-91 °C (lit.) | |
pH | 9.5-11.0 (25 °C, 50 mg/mL in H2O) |
pKa (25 °C) | 6.95 |
Quality Level | 200 ![]() |
SMILES string | c1c[nH]cn1 |
solubility | alcohol: soluble(lit.) |
chloroform: soluble(lit.) | |
pyridine: soluble(lit.) | |
water: soluble(lit.) | |
vapor pressure | <1 mmHg ( 20 °C) |
Application: | Excellent for buffers in the range of pH 6.2-7.8 |
Application: | Imidazole can be used as a catalyst: • For the silylation of alcohols, carboxylic acids, and amines in the presence of silyl chloride in DMF. • In the peptide coupling using the triphenyl phosphite. • To prepare acid chlorides from the corresponding carboxylic acids and phosgene. It can also be used in the following reactions: • Imidazole-PPh3/I2 catalytic system used in the conversion of alcohols into iodides • Imidazole-PPh3/I2 is used in the diol deoxygenation reaction. |
General description: | Imidazole is an aromatic heterocyclic compound with a five-membered planar ring. It is an amphoteric compound because of the presence of both an acidic NH and a basic nitrogen atom. Imidazole is an essential component of many important molecules including natural products, bioactive molecules, ionic liquids, and imidazolium. |
Other Notes: | For titration of aspartic acid and glutamic acid |
Packaging: | 1 kg in poly bottle |
Packaging: | 100, 500 g in poly bottle |
Symbol | ![]() ![]() ![]() |
Signal word | Danger |
Hazard statements | H302 - H314 - H360D |
Precautionary statements | P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
Hazard Codes | T |
Risk Statements | 61-22-34 |
Safety Statements | 53-26-36/37/39-45 |
RIDADR | UN 3263 8 / PGIII |
WGK Germany | WGK 2 |
Flash Point(F) | 293.0 °F - closed cup |
Flash Point(C) | 145 °C - closed cup |
Purity | ≥99.5% (GC) |
bp | 256 °C (lit.) |
mp | 88-91 °C (lit.); 88-91 °C |
UNSPSC | 12352005 |