Chlorosulfonic acid
SIAL/571024 - 99%
Synonym: Sulfuric chlorohydrin
CAS Number: 7790-94-5
Empirical Formula (Hill Notation): HClO3S
Molecular Weight: 116.52
EC Number: 232-234-6
MDL Number: MFCD00011523
Linear Formula: ClSO3H
Product Type: Chemical
assay | 99% |
bp | 151-152 °C/755 mmHg (lit.) |
density | 1.753 g/mL at 25 °C (lit.) |
expl. lim. | 37.7 % |
InChI | 1S/ClHO3S/c1-5(2,3)4/h(H, |
InChI key | XTHPWXDJESJLNJ-UHFFFAOYSA |
Quality Level | 200 ![]() |
refractive index | n |
SMILES string | OS(Cl)(=O)=O |
solubility | acetic acid: soluble(lit.) |
chloroform: soluble(lit.) | |
dichloromethane: soluble(lit.) | |
vapor density | 4 (vs air) |
vapor pressure | 1 mmHg ( 25 °C) |
3.3 mmHg ( 37.7 °C) |
Application: | Chlorosulfonic acid may be used in the following processes: • Synthesis of di-n-butyl ammonium chlorosulfonate, a secondary amine ionic liquid. • To prepare sulfonated polyethersulfone (SPES) with enhanced hydrophilic property. • To attach sulfate group to silk fibroin for improving its anticoagulant ability. • As a catalyst to prepare substituted coumarin, via von Pechmann condensation between phenol and β-ketoester. • As a substitute to acid catalyst in Biginelli reaction to prepare 3,4dihydropyrimidines. |
General description: | Chlorosulfonic acid is a strong acid that is synthesized on an industrial scale by reacting sulfur trioxide and dry hydrogen chloride gas in an equimolar ratio. It can act as a sulfonating, dehydrating, oxidizing and chlorinating agent. It is reported to be a better electrophilic olefin cyclization agent in comparison to other sulfonic acids. Its infrared spectra in the solid, liquid and gaseous state have been recorded in the region 4000-400cm-1. |
Packaging: | 1 kg in glass bottle |
Packaging: | 5, 100, 4×100 g in glass bottle |
Packaging: | View returnable container options ![]() |
Symbol | ![]() ![]() |
Signal word | Danger |
Hazard statements | H314 - H330 - H335 |
Precautionary statements | P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
Hazard Codes | C |
Risk Statements | 14-35-37 |
Safety Statements | 26-45 |
RIDADR | UN 1754 8 / PGI |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Supplemental Hazard Statements | EUH014 |
Purity | 99% |
bp | 151-152 °C/755 mmHg (lit.) |
Density | 1.753 g/mL at 25 °C (lit.) |
Refractive Index | n |
UNSPSC | 12352100 |