Losartan potassium
SIAL/61188
Synonym: 2-
CAS Number: 124750-99-8
Empirical Formula (Hill Notation): C22H22ClKN6O
Molecular Weight: 461.00
MDL Number: MFCD02092704
Linear Formula: C22H22ClKN6O
Product Type: Chemical
application(s) | forensics and toxicology pharmaceutical (small molecule) veterinary |
form | powder or crystals |
impurities | ≤0.5% water |
InChI | 1S/C22H22ClN6O.K/c1-2-3-8 |
InChI key | OXCMYAYHXIHQOA-UHFFFAOYSA |
Quality Level | 200 ![]() |
shelf life | limited shelf life, expiry date on the label |
SMILES string | CCCCc1nc(Cl)c(CO)n1Cc2ccc |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Application: | Losartan potassium may be used as an analytical reference standard for the quantification of the analyte in the following: • Pharmaceutical formulations using reversed-phase high-performance liquid chromatography and UV-spectrophotometric techniques. • Rat plasma using liquid chromatography–tandem mass spectrometry (LC–MS/MS) technique. |
Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
Biochem/physiol Actions: | Losartan potassium is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan potassium is used for treatment of hypertension. |
General description: | Losartan potassium has long lasting effects, and its efficacy is generally increased, when combined with the diuretic co-active hydrochlorothiazide. |
General description: | Losartan potassium is an antihypertensive drug that is found to be an angiotensin II receptor type 1 blocker. It finds applications in reducing mechanical stress thereby having a control over the condition of cardiac hypertrophy. |
Packaging: | 100 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
UNSPSC | 41116107 |