α-Ketoglutaric acid
SIAL/61234 - analytical standard
Synonym: 2-Oxoglutaric acid; 2-Oxopentanedioic acid
CAS Number: 328-50-7
Empirical Formula (Hill Notation): C5H6O5
Molecular Weight: 146.10
EC Number: 206-330-3
MDL Number: MFCD00004165
Linear Formula: HOOCCH2CH2COCOOH
Product Type: Chemical
application(s) | clinical testing |
assay | 99.0-101.0% (T) |
format | neat |
grade | analytical standard |
InChI | 1S/C5H6O5/c6-3(5(9)10)1-2 |
InChI key | KPGXRSRHYNQIFN-UHFFFAOYSA |
shelf life | limited shelf life, expiry date on the label |
SMILES string | OC(=O)CCC(=O)C(O)=O |
storage temp. | 2-8°C |
Application: | α-Ketoglutaric acid may be used as an analytical reference standard for the quantification of the analyte in the following: • Human plasma samples using gas-chromatography coupled to mass spectrometry. • Beer samples using high-performance liquid chromatography with UV detection, and further confirmed by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). • Fruits and vegetables using HPLC-MS/MS. |
General description: | α-Ketoglutaric acid, an α-ketoacid, is identified as a potential, renal cell carcinoma (RCC) biomarker via urinary metabolomic profiling. It plays an important role in living beings as an angiogenesis suppressor. |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H318 |
Precautionary statements | P280 - P305 + P351 + P338 + P310 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 99.0-101.0% (T) |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |