4-Maleimidobutyric acid
SIAL/63174 - ≥98.0% (T)
Synonym: γ-Maleimidobutyric acid; 4-Maleimidobutanoic acid; N-
CAS Number: 57078-98-5
Empirical Formula (Hill Notation): C8H9NO4
Molecular Weight: 183.16
MDL Number: MFCD00043139
Linear Formula: C8H9NO4
Product Type: Chemical
| assay | ≥98.0% (T) |
| InChI | 1S/C8H9NO4/c10-6-3-4-7(11 |
| InChI key | NCPQROHLJFARLL-UHFFFAOYSA |
| mp | 95-98 °C |
| Quality Level | 100 ![]() |
| SMILES string | OC(=O)CCCN1C(=O)C=CC1=O |
| Application: | Gamma-maleimidobutyric acid may be used as a spacer in the construction of drug and other types of bioconjugates. 4-Maleimidobutyric acid is used with N-hydroxysuccinimide ester as a bifunctional cross-linking agent. |
| Application: | Modification reagent for thiol groups in proteins |
| Other Notes: | SH-label for the modification of peptides and proteins; Used for the preparation of a new bleomycin analog for enzyme immunoassay (EIA); probe for membrane SH-groups |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.0% (T) |
| mp | 95-98 °C |
| UNSPSC | 12352106 |


